Motor Skill Acquisition Promotes Human Brain Myelin Plasticity
Joint Authors
Boyd, Lara A.
Peters, Sue
Lakhani, Bimal
Borich, Michael R.
Jackson, Jacob N.
Wadden, Katie P.
Villamayor, Anica
MacKay, Alex L.
Vavasour, Irene M.
Rauscher, Alexander
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Experience-dependent structural changes are widely evident in gray matter.
Using diffusion weighted imaging (DWI), the neuroplastic effect of motor training on white matter in the brain has been demonstrated.
However, in humans it is not known whether specific features of white matter relate to motor skill acquisition or if these structural changes are associated to functional network connectivity.
Myelin can be objectively quantified in vivo and used to index specific experience-dependent change.
In the current study, seventeen healthy young adults completed ten sessions of visuomotor skill training (10,000 total movements) using the right arm.
Multicomponent relaxation imaging was performed before and after training.
Significant increases in myelin water fraction, a quantitative measure of myelin, were observed in task dependent brain regions (left intraparietal sulcus [IPS] and left parieto-occipital sulcus).
In addition, the rate of motor skill acquisition and overall change in myelin water fraction in the left IPS were negatively related, suggesting that a slower rate of learning resulted in greater neuroplastic change.
This study provides the first evidence for experience-dependent changes in myelin that are associated with changes in skilled movements in healthy young adults.
American Psychological Association (APA)
Lakhani, Bimal& Borich, Michael R.& Jackson, Jacob N.& Wadden, Katie P.& Peters, Sue& Villamayor, Anica…[et al.]. 2016. Motor Skill Acquisition Promotes Human Brain Myelin Plasticity. Neural Plasticity،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1113279
Modern Language Association (MLA)
Lakhani, Bimal…[et al.]. Motor Skill Acquisition Promotes Human Brain Myelin Plasticity. Neural Plasticity No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1113279
American Medical Association (AMA)
Lakhani, Bimal& Borich, Michael R.& Jackson, Jacob N.& Wadden, Katie P.& Peters, Sue& Villamayor, Anica…[et al.]. Motor Skill Acquisition Promotes Human Brain Myelin Plasticity. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1113279
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113279