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Traumatic Brain Injury and Substance Related Disorder: A 10-Year Nationwide Cohort Study in Taiwan
Joint Authors
Lin, Chih-Lung
Tsai, Tai-Hsin
Zhang, Zi-Hao
Liu, Wei
Wu, Ming-Kung
Chang, Chih-Hui
Kuo, Keng-Liang
Lu, Ying-Yi
Su, Yu-Feng
Wu, Chieh Hsin
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-27
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Whether traumatic brain injury (TBI) is causally related to substance related disorder (SRD) is still debatable, especially in persons with no history of mental disorders at the time of injury.
This study analyzed data in the Taiwan National Health Insurance Research Database for 19,109 patients aged ≥18 years who had been diagnosed with TBI during 2000–2010.
An additional 19,109 randomly selected age and gender matched patients without TBI (1 : 1 ratio) were enrolled in the control group.
The relationship between TBI and SRD was estimated with Cox proportional hazard regression models.
During the follow-up period, SRD developed in 340 patients in the TBI group and in 118 patients in the control group.
After controlling for covariates, the overall incidence of SRD was 3.62-fold higher in the TBI group compared to the control group.
Additionally, patients in the severe TBI subgroup were 9.01 times more likely to have SRD compared to controls.
Notably, patients in the TBI group were prone to alcohol related disorders.
The data in this study indicate that TBI is significantly associated with the subsequent risk of SRD.
Physicians treating patients with TBI should be alert to this association to prevent the occurrence of adverse events.
American Psychological Association (APA)
Wu, Chieh Hsin& Tsai, Tai-Hsin& Su, Yu-Feng& Zhang, Zi-Hao& Liu, Wei& Wu, Ming-Kung…[et al.]. 2016. Traumatic Brain Injury and Substance Related Disorder: A 10-Year Nationwide Cohort Study in Taiwan. Neural Plasticity،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113294
Modern Language Association (MLA)
Wu, Chieh Hsin…[et al.]. Traumatic Brain Injury and Substance Related Disorder: A 10-Year Nationwide Cohort Study in Taiwan. Neural Plasticity No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1113294
American Medical Association (AMA)
Wu, Chieh Hsin& Tsai, Tai-Hsin& Su, Yu-Feng& Zhang, Zi-Hao& Liu, Wei& Wu, Ming-Kung…[et al.]. Traumatic Brain Injury and Substance Related Disorder: A 10-Year Nationwide Cohort Study in Taiwan. Neural Plasticity. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113294
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113294