![](/images/graphics-bg.png)
BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal
Joint Authors
Source
Neurology Research International
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
Nondiabetic obese individuals have subclinical involvement of peripheral nerves.
We report the factors predicting peripheral nerve function in overweight and obese nondiabetic Nepalese individuals.
Methodology.
In this cross-sectional study, we included 50 adult overweight and obese nondiabetic volunteers without features of peripheral neuropathy and 50 healthy volunteers to determine the normative nerve conduction data.
In cases of abnormal function, the study population was classified on the basis of the number of nerves involved, namely, “<2” or “≥2.” Multivariable logistic regression analysis was carried out to predict outcomes.
Results.
Fasting blood glucose (FBG) was the significant predictor of motor nerve dysfunction (P=0.039, 95% confidence interval (CI) = 1.003–1.127).
Homeostatic model assessment of insulin resistance (HOMA-IR) was the significant predictor (P=0.019, 96% CI = 1.420–49.322) of sensory nerve dysfunction.
Body mass index (BMI) was the significant predictor (P=0.034, 95% CI = 1.018–1.577) in case of ≥2 mixed nerves’ involvement.
Conclusion.
FBG, HOMA-IR, and BMI were significant predictors of peripheral nerve dysfunction in overweight and obese Nepalese individuals.
American Psychological Association (APA)
Thapa, Lekhjung& Rana, P. V. S.. 2016. BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal. Neurology Research International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113427
Modern Language Association (MLA)
Thapa, Lekhjung& Rana, P. V. S.. BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal. Neurology Research International No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1113427
American Medical Association (AMA)
Thapa, Lekhjung& Rana, P. V. S.. BMI, HOMA-IR, and Fasting Blood Glucose Are Significant Predictors of Peripheral Nerve Dysfunction in Adult Overweight and Obese Nondiabetic Nepalese Individuals: A Study from Central Nepal. Neurology Research International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1113427
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113427