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Peripheral Nerve Ultrasonography in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy: Correlations with Clinical and Neurophysiological Data
Joint Authors
Merola, Aristide
Rosso, Michela
Romagnolo, Alberto
Peci, Erdita
Cocito, Dario
Source
Neurology Research International
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
This cross-sectional study analyzes the pattern of ultrasound peripheral nerve alterations in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multifocal motor neuropathy (MMN) at different stages of functional disability.
Material and Methods.
22 CIDP and 10 MMN patients and a group of 70 healthy controls were evaluated with an ultrasound scan of the median, ulnar, peroneal, tibial, and sural nerves.
Results were correlated with clinical disability scales and nerve conduction studies.
Results.
Patients with intermediate functional impairment showed relatively larger cross-sectional areas than subjects with either a milder ( p < 0.05 ) or more severe impairment ( p < 0.05 ), both in CIDP and in MMN.
In addition, MMN was associated with greater side-to-side intranerve variability ( p < 0.05 ), while higher cross-sectional areas were observed in CIDP ( p < 0.05 ) and in nerve segments with predominantly demyelinating features ( p < 0.05 ).
Higher CSA values were observed in nerves with demyelinating features versus axonal damage ( p < 0.05 for CIDP; p < 0.05 for MMN).
Discussion and Conclusions.
Greater extent of quantitative and qualitative US alterations was observed in patients at intermediate versus higher functional disability and in nerves with demyelinating versus axonal damage.
CIDP and MMN showed differential US aspects, with greater side-to-side intranerve variability in MMN and higher cross-sectional areas in CIDP.
American Psychological Association (APA)
Merola, Aristide& Rosso, Michela& Romagnolo, Alberto& Peci, Erdita& Cocito, Dario. 2016. Peripheral Nerve Ultrasonography in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy: Correlations with Clinical and Neurophysiological Data. Neurology Research International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1113439
Modern Language Association (MLA)
Merola, Aristide…[et al.]. Peripheral Nerve Ultrasonography in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy: Correlations with Clinical and Neurophysiological Data. Neurology Research International No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1113439
American Medical Association (AMA)
Merola, Aristide& Rosso, Michela& Romagnolo, Alberto& Peci, Erdita& Cocito, Dario. Peripheral Nerve Ultrasonography in Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy: Correlations with Clinical and Neurophysiological Data. Neurology Research International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1113439
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113439