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Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy
Joint Authors
Duan, Xiaochun
Wen, Zunjia
Shen, Haitao
Shen, Meifen
Hang, Chunhua
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-14
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Hemorrhagic stroke is a common and severe neurological disorder and is associated with high rates of mortality and morbidity, especially for intracerebral hemorrhage (ICH).
Increasing evidence demonstrates that oxidative stress responses participate in the pathophysiological processes of secondary brain injury (SBI) following ICH.
The mechanisms involved in interoperable systems include endoplasmic reticulum (ER) stress, neuronal apoptosis and necrosis, inflammation, and autophagy.
In this review, we summarized some promising advances in the field of oxidative stress and ICH, including contained animal and human investigations.
We also discussed the role of oxidative stress, systemic oxidative stress responses, and some research of potential therapeutic options aimed at reducing oxidative stress to protect the neuronal function after ICH, focusing on the challenges of translation between preclinical and clinical studies, and potential post-ICH antioxidative therapeutic approaches.
American Psychological Association (APA)
Duan, Xiaochun& Wen, Zunjia& Shen, Haitao& Shen, Meifen& Hang, Chunhua. 2016. Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-17.
https://search.emarefa.net/detail/BIM-1113597
Modern Language Association (MLA)
Duan, Xiaochun…[et al.]. Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-17.
https://search.emarefa.net/detail/BIM-1113597
American Medical Association (AMA)
Duan, Xiaochun& Wen, Zunjia& Shen, Haitao& Shen, Meifen& Hang, Chunhua. Intracerebral Hemorrhage, Oxidative Stress, and Antioxidant Therapy. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-17.
https://search.emarefa.net/detail/BIM-1113597
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113597