Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage
Joint Authors
Hernández, José A.
López-Sánchez, Rosa C.
Rendón-Ramírez, Adela
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-05
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
The excessive intake of alcohol is a serious public health problem, especially given the severe damage provoked by chronic or prenatal exposure to alcohol that affects many physiological processes, such as memory, motor function, and cognitive abilities.
This damage is related to the ethanol oxidation in the brain.
The metabolism of ethanol to acetaldehyde and then to acetate is associated with the production of reactive oxygen species that accentuate the oxidative state of cells.
This metabolism of ethanol can induce the oxidation of the fatty acids in phospholipids, and the bioactive aldehydes produced are known to be associated with neurotoxicity and neurodegeneration.
As such, here we will review the role of lipids in the neuronal damage induced by ethanol-related oxidative stress and the role that lipids play in the related compensatory or defense mechanisms.
American Psychological Association (APA)
Hernández, José A.& López-Sánchez, Rosa C.& Rendón-Ramírez, Adela. 2016. Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1113625
Modern Language Association (MLA)
Hernández, José A.…[et al.]. Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1113625
American Medical Association (AMA)
Hernández, José A.& López-Sánchez, Rosa C.& Rendón-Ramírez, Adela. Lipids and Oxidative Stress Associated with Ethanol-Induced Neurological Damage. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1113625
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113625