Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice
Joint Authors
Guo, Jiaming
Zhao, Deyun
Lei, Xiao
Zhao, Hainan
Yang, Yanyong
Zhang, Pei
Liu, Pengfei
Xu, Yang
Zhu, Meizhou
Liu, Hu
Chen, Yuanyuan
Chuai, Yunhai
Li, Bailong
Gao, Fu
Cai, Jianming
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-27
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Molecular hydrogen ( H 2 ) has been previously reported playing an important role in ameliorating damage caused by acute radiation.
In this study, we investigated the effects of H 2 on the alterations induced by low-dose long-term radiation (LDLTR).
All the mice in hydrogen-treated or radiation-only groups received 0.1 Gy, 0.5 Gy, 1.0 Gy, and 2.0 Gy whole-body gamma radiation, respectively.
After the last time of radiation exposure, all the mice were employed for the determination of the body mass (BM) observation, forced swim test (FST), the open field test (OFT), the chromosome aberration (CA), the peripheral blood cells parameters analysis, the sperm abnormality (SA), the lymphocyte transformation test (LTT), and the histopathological studies.
And significant differences between the treatment group and the radiation-only groups were observed, showing that H 2 could diminish the detriment induced by LDLTR and suggesting the protective efficacy of H 2 in multiple systems in mice against LDLTR.
American Psychological Association (APA)
Guo, Jiaming& Zhao, Deyun& Lei, Xiao& Zhao, Hainan& Yang, Yanyong& Zhang, Pei…[et al.]. 2016. Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1113662
Modern Language Association (MLA)
Guo, Jiaming…[et al.]. Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1113662
American Medical Association (AMA)
Guo, Jiaming& Zhao, Deyun& Lei, Xiao& Zhao, Hainan& Yang, Yanyong& Zhang, Pei…[et al.]. Protective Effects of Hydrogen against Low-Dose Long-Term Radiation-Induced Damage to the Behavioral Performances, Hematopoietic System, Genital System, and Splenic Lymphocytes in Mice. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1113662
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113662