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Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus
Joint Authors
Yang, Xue
Yang, Ji
Li, Ming
Zou, He-Jian
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-11
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Systemic lupus erythematosus (SLE) is an autoimmune disease that involves multiple organ systems.
The pathogenic mechanisms that cause SLE remain unclear; however, it is well recognized that the immune balance is disturbed and that this imbalance contributes to the autoimmune symptoms of SLE.
Oxidative stress represents an imbalance between the production and manifestation of reactive oxygen species and the ability of the biological system to readily detoxify the reactive intermediates or to repair the resulting damage.
In humans, oxidative stress is involved in many diseases, including atherosclerosis, myocardial infarction, and autoimmune diseases.
Numerous studies have confirmed that oxidative stress plays an important role in the pathogenesis of SLE.
This review mainly focuses on the recent research advances with respect to oxidative stress and regulatory T (Treg)/helper T 17 (Th17) cell dysfunction in the pathogenesis of SLE.
American Psychological Association (APA)
Yang, Ji& Yang, Xue& Zou, He-Jian& Li, Ming. 2016. Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1113715
Modern Language Association (MLA)
Yang, Ji…[et al.]. Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1113715
American Medical Association (AMA)
Yang, Ji& Yang, Xue& Zou, He-Jian& Li, Ming. Oxidative Stress and Treg and Th17 Dysfunction in Systemic Lupus Erythematosus. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1113715
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113715