Longxuetongluo Capsule Improves Erythrocyte Function against Lipid Peroxidation and Abnormal Hemorheological Parameters in High Fat Diet-Induced ApoE−− Mice
Joint Authors
Yao, Wei-Juan
Zheng, Jiao
Liu, Binglin
Lun, Qixing
Zhao, Yunfang
Xiao, Wei
Huang, Wenzhe
Li, Jun
Tu, Pengfei
Wang, Yonghua
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-11-16
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Chinese dragon’s blood, the red resin of Dracaena cochinchinensis, one of the renowned traditional medicines, has been used to facilitate blood circulation and disperse blood stasis for thousands of years.
Phenolic compounds are considered to be responsible for its main biological activities.
In this study, total phenolic compounds of Chinese dragon’s blood were made into capsule (Longxuetongluo Capsule, LTC) and their effects on the abnormal hemorheological properties were examined by high fat diet (HFD) induced ApoE−/− mice.
Compared to the model group, LTC recovered the abnormal hemorheological parameters in HFD-induced ApoE−/− mice by reducing whole blood viscosity (WBV) at high rate and improving erythrocyte function.
In conclusion, LTC could ameliorate erythrocyte deformability and osmotic fragility through the reduction of lipid peroxidation on plasma and erythrocyte membranes in HFD-induced ApoE−/− mice, which supported the traditional uses of Chinese dragon’s blood as an effective agent for improving blood microcirculation in hypercholesterolemia.
American Psychological Association (APA)
Zheng, Jiao& Liu, Binglin& Lun, Qixing& Yao, Wei-Juan& Zhao, Yunfang& Xiao, Wei…[et al.]. 2015. Longxuetongluo Capsule Improves Erythrocyte Function against Lipid Peroxidation and Abnormal Hemorheological Parameters in High Fat Diet-Induced ApoE−− Mice. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113730
Modern Language Association (MLA)
Zheng, Jiao…[et al.]. Longxuetongluo Capsule Improves Erythrocyte Function against Lipid Peroxidation and Abnormal Hemorheological Parameters in High Fat Diet-Induced ApoE−− Mice. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1113730
American Medical Association (AMA)
Zheng, Jiao& Liu, Binglin& Lun, Qixing& Yao, Wei-Juan& Zhao, Yunfang& Xiao, Wei…[et al.]. Longxuetongluo Capsule Improves Erythrocyte Function against Lipid Peroxidation and Abnormal Hemorheological Parameters in High Fat Diet-Induced ApoE−− Mice. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1113730
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113730