Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study
Joint Authors
Trukhanov, Arseny
Korkina, Liudmila
Mikhal’chik, Elena V.
Suprun, Maxim V.
Papacharalambous, Michael
De Luca, Chiara
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-19
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Recently, development and research of nutraceuticals based on marine collagen peptides (MCPs) have been growing due to their high homology with human collagens, safety, bioavailability through gut, and numerous bioactivities.
The major concern regarding safety of MCPs intake relates to increased risk of oxidative stress connected with collagen synthesis (likewise in fibrosis) and to ROS production by MCPs-stimulated phagocytes.
In this clinical-laboratory study, fish skin MCPs combined with plant-derived skin-targeting antioxidants (AO) (coenzyme Q10 + grape-skin extract + luteolin + selenium) were administered to volunteers (n=41).
Skin properties (moisture, elasticity, sebum production, and biological age) and ultrasonic markers (epidermal/dermal thickness and acoustic density) were measured thrice (2 months before treatment and before and after cessation of 2-month oral intake).
The supplementation remarkably improved skin elasticity, sebum production, and dermal ultrasonic markers.
Metabolic data showed significant increase of plasma hydroxyproline and ATP storage in erythrocytes.
Redox parameters, GSH/coenzyme Q10 content, and GPx/GST activities were unchanged, while NO and MDA were moderately increased within, however, normal range of values.
Conclusions.
A combination of MCPs with skin-targeting AOs could be effective and safe supplement to improve skin properties without risk of oxidative damage.
American Psychological Association (APA)
De Luca, Chiara& Mikhal’chik, Elena V.& Suprun, Maxim V.& Papacharalambous, Michael& Trukhanov, Arseny& Korkina, Liudmila. 2016. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1113923
Modern Language Association (MLA)
De Luca, Chiara…[et al.]. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-14.
https://search.emarefa.net/detail/BIM-1113923
American Medical Association (AMA)
De Luca, Chiara& Mikhal’chik, Elena V.& Suprun, Maxim V.& Papacharalambous, Michael& Trukhanov, Arseny& Korkina, Liudmila. Skin Antiageing and Systemic Redox Effects of Supplementation with Marine Collagen Peptides and Plant-Derived Antioxidants: A Single-Blind Case-Control Clinical Study. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-14.
https://search.emarefa.net/detail/BIM-1113923
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1113923