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Relationship between the Peroxidation of Leukocytes Index Ratio and the Improvement of Postprandial Metabolic Stress by a Functional Food
Joint Authors
Peluso, Ilaria
Palmery, Maura
Manafikhi, Husseen
Reggi, Raffaella
Longhitano, Yaroslava
Zanza, Christian
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-28
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
For the first time, we investigated the relationship between postprandial dysmetabolism and the Peroxidation of Leukocytes Index Ratio (PLIR), a test that measures the resistance of leukocytes to exogenous oxidative stress and their functional capacity of oxidative burst upon activation.
Following a blind, placebo controlled, randomized, crossover design, ten healthy subjects ingested, in two different occasions, a high fat and high carbohydrates meal with Snello cookie (HFHCM-S) or with control cookies (HFHCM-C).
Snello cookie, a functional food covered by dark chocolate and containing glucomannan, inulin, fructooligosaccharides, and Bacillus coagulans strain GanedenBC30, significantly improved postprandial metabolic stress (insulin, glucose, and triglycerides) and reduced the postprandial increase of uric acid.
HFHCM-S improved PLIR of lymphocytes, but not of monocytes and granulocytes.
Both meals increased granulocytes’ count and reduced the lipoperoxidation induced by both exogenous free radicals and reactive oxygen species (ROS) produced by oxidative burst.
Our results suggest that the healthy status of the subjects could be a limitation of this pilot study for PLIR evaluation on cells that produce ROS by oxidative burst.
In conclusion, the relationship between PLIR and postprandial dysmetabolism requires further investigations.
American Psychological Association (APA)
Peluso, Ilaria& Manafikhi, Husseen& Reggi, Raffaella& Longhitano, Yaroslava& Zanza, Christian& Palmery, Maura. 2015. Relationship between the Peroxidation of Leukocytes Index Ratio and the Improvement of Postprandial Metabolic Stress by a Functional Food. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1114030
Modern Language Association (MLA)
Peluso, Ilaria…[et al.]. Relationship between the Peroxidation of Leukocytes Index Ratio and the Improvement of Postprandial Metabolic Stress by a Functional Food. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1114030
American Medical Association (AMA)
Peluso, Ilaria& Manafikhi, Husseen& Reggi, Raffaella& Longhitano, Yaroslava& Zanza, Christian& Palmery, Maura. Relationship between the Peroxidation of Leukocytes Index Ratio and the Improvement of Postprandial Metabolic Stress by a Functional Food. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1114030
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114030