Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?
Author
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Oxidative stress has been implicated in many chronic diseases.
However, antioxidant trials are so far largely unsuccessful as a preventive or curative measure.
Chronic low-grade inflammatory process, on the other hand, plays a central role in the pathogenesis of a number of chronic diseases.
Oxidative stress and inflammation are closely related pathophysiological processes, one of which can be easily induced by another.
Thus, both processes are simultaneously found in many pathological conditions.
Therefore, the failure of antioxidant trials might result from failure to select appropriate agents that specifically target both inflammation and oxidative stress or failure to use both antioxidants and anti-inflammatory agents simultaneously or use of nonselective agents that block some of the oxidative and/or inflammatory pathways but exaggerate the others.
To examine whether the interdependence between oxidative stress and inflammation can explain the antioxidant paradox we discussed in the present review the basic aspects of oxidative stress and inflammation and their relationship and dependence.
American Psychological Association (APA)
Biswas, Subrata Kumar. 2016. Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114036
Modern Language Association (MLA)
Biswas, Subrata Kumar. Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1114036
American Medical Association (AMA)
Biswas, Subrata Kumar. Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114036
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114036