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Correlation of Oxidative and Antioxidative Processes in the Blood of Patients with Cervical Spinal Cord Injury
Joint Authors
Woźniak, Alina
Kasprzak, Heliodor Adam
Mila-Kierzenkowska, Celestyna
Woźniak, Bartosz
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The effect of cervical spinal cord injury (CSCI) on oxidative stress parameters was assessed.
The study was conducted in 42 patients with CSCI (studied group), 15 patients with cerebral concussion, without CSCI (Control II), and 30 healthy volunteers (Control I).
Blood was taken from the basilic vein: before and seven days after the spinal cord decompression surgery (mean time from CSCI to surgery: 8 hours) in the studied group and once in the controls.
Thiobarbituric acid reactive substances (TBARS) and conjugated dienes (CD) concentrations, and glutathione peroxidase (GPx), catalase (CAT), and creatine kinase (CK) activities before the surgery were higher in the studied group than in the controls.
Reduced glutathione concentration was similar in all groups.
Superoxide dismutase (SOD) in the studied group was 16% lower ( P ≤ 0.001 ) than in Control I.
Lipid peroxidation products, and GPx and CAT activities in erythrocytes seven days after the surgery were lower ( P ≤ 0.001 ), while SOD was 25% higher ( P ≤ 0.001 ) than before the surgery.
CK in blood plasma after the surgery was 34% lower ( P ≤ 0.001 ) than before it.
CSCI is accompanied by oxidative stress.
Surgical and pharmacological treatment helps to restore the oxidant-antioxidant balance.
American Psychological Association (APA)
Woźniak, Bartosz& Woźniak, Alina& Mila-Kierzenkowska, Celestyna& Kasprzak, Heliodor Adam. 2016. Correlation of Oxidative and Antioxidative Processes in the Blood of Patients with Cervical Spinal Cord Injury. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114083
Modern Language Association (MLA)
Woźniak, Bartosz…[et al.]. Correlation of Oxidative and Antioxidative Processes in the Blood of Patients with Cervical Spinal Cord Injury. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1114083
American Medical Association (AMA)
Woźniak, Bartosz& Woźniak, Alina& Mila-Kierzenkowska, Celestyna& Kasprzak, Heliodor Adam. Correlation of Oxidative and Antioxidative Processes in the Blood of Patients with Cervical Spinal Cord Injury. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114083
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114083