DNA Tumor Viruses and Cell Metabolism
Joint Authors
Mushtaq, Muhammad
Darekar, Suhas
Kashuba, Elena
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-29
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Viruses play an important role in cancerogenesis.
It is estimated that approximately 20% of all cancers are linked to infectious agents.
The viral genes modulate the physiological machinery of infected cells that lead to cell transformation and development of cancer.
One of the important adoptive responses by the cancer cells is their metabolic change to cope up with continuous requirement of cell survival and proliferation.
In this review we will focus on how DNA viruses alter the glucose metabolism of transformed cells.
Tumor DNA viruses enhance “aerobic” glycolysis upon virus-induced cell transformation, supporting rapid cell proliferation and showing the Warburg effect.
Moreover, viral proteins enhance glucose uptake and controls tumor microenvironment, promoting metastasizing of the tumor cells.
American Psychological Association (APA)
Mushtaq, Muhammad& Darekar, Suhas& Kashuba, Elena. 2016. DNA Tumor Viruses and Cell Metabolism. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114117
Modern Language Association (MLA)
Mushtaq, Muhammad…[et al.]. DNA Tumor Viruses and Cell Metabolism. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1114117
American Medical Association (AMA)
Mushtaq, Muhammad& Darekar, Suhas& Kashuba, Elena. DNA Tumor Viruses and Cell Metabolism. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1114117
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114117
