Redox Imbalance and Viral Infections in Neurodegenerative Diseases
Joint Authors
Limongi, Dolores
Baldelli, Sara
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-27
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Reactive oxygen species (ROS) are essential molecules for many physiological functions and act as second messengers in a large variety of tissues.
An imbalance in the production and elimination of ROS is associated with human diseases including neurodegenerative disorders.
In the last years the notion that neurodegenerative diseases are accompanied by chronic viral infections, which may result in an increase of neurodegenerative diseases progression, emerged.
It is known in literature that enhanced viral infection risk, observed during neurodegeneration, is partly due to the increase of ROS accumulation in brain cells.
However, the molecular mechanisms of viral infection, occurring during the progression of neurodegeneration, remain unclear.
In this review, we discuss the recent knowledge regarding the role of influenza, herpes simplex virus type-1, and retroviruses infection in ROS/RNS-mediated Parkinson’s disease (PD), Alzheimer’s disease (AD), and amyotrophic lateral sclerosis (ALS).
American Psychological Association (APA)
Limongi, Dolores& Baldelli, Sara. 2016. Redox Imbalance and Viral Infections in Neurodegenerative Diseases. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1114124
Modern Language Association (MLA)
Limongi, Dolores& Baldelli, Sara. Redox Imbalance and Viral Infections in Neurodegenerative Diseases. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-13.
https://search.emarefa.net/detail/BIM-1114124
American Medical Association (AMA)
Limongi, Dolores& Baldelli, Sara. Redox Imbalance and Viral Infections in Neurodegenerative Diseases. Oxidative Medicine and Cellular Longevity. 2016. Vol. 2016, no. 2016, pp.1-13.
https://search.emarefa.net/detail/BIM-1114124
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114124