Effects of Hyperoxia on Oxygen-Related Inflammation with a Focus on Obesity
Joint Authors
González-Muniesa, Pedro
Garcia-Gerique, Laura
Quintero, Pablo
Arriaza, Suyen
Lopez-Pascual, Amaya
Martínez, J. Alfredo
Source
Oxidative Medicine and Cellular Longevity
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2015-12-01
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Several studies have shown a pathological oxygenation (hypoxia/hyperoxia) on the adipose tissue in obese subjects.
Additionally, the excess of body weight is often accompanied by a state of chronic low-degree inflammation.
The inflammation phenomenon is a complex biological response mounted by tissues to combat injurious stimuli in order to maintain cell homeostasis.
Furthermore, it is believed that the abnormal oxygen partial pressure occurring in adipose tissue is involved in triggering inflammatory processes.
In this context, oxygen is used in modern medicine as a treatment for several diseases with inflammatory components.
Thus, hyperbaric oxygenation has demonstrated beneficial effects, apart from improving local tissue oxygenation, on promoting angiogenesis, wound healing, providing neuroprotection, facilitating glucose uptake, appetite, and others.
Nevertheless, an excessive hyperoxia exposure can lead to deleterious effects such as oxidative stress, pulmonary edema, and maybe inflammation.
Interestingly, some of these favorable outcomes occur under high and low oxygen concentrations.
Hereby, we review a potential therapeutic approach to the management of obesity as well as the oxygen-related inflammation accompanying expanded adipose tissue, based on elevated oxygen concentrations.
To conclude, we highlight at the end of this review some areas that need further clarification.
American Psychological Association (APA)
González-Muniesa, Pedro& Garcia-Gerique, Laura& Quintero, Pablo& Arriaza, Suyen& Lopez-Pascual, Amaya& Martínez, J. Alfredo. 2015. Effects of Hyperoxia on Oxygen-Related Inflammation with a Focus on Obesity. Oxidative Medicine and Cellular Longevity،Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1114475
Modern Language Association (MLA)
González-Muniesa, Pedro…[et al.]. Effects of Hyperoxia on Oxygen-Related Inflammation with a Focus on Obesity. Oxidative Medicine and Cellular Longevity No. 2016 (2016), pp.1-11.
https://search.emarefa.net/detail/BIM-1114475
American Medical Association (AMA)
González-Muniesa, Pedro& Garcia-Gerique, Laura& Quintero, Pablo& Arriaza, Suyen& Lopez-Pascual, Amaya& Martínez, J. Alfredo. Effects of Hyperoxia on Oxygen-Related Inflammation with a Focus on Obesity. Oxidative Medicine and Cellular Longevity. 2015. Vol. 2016, no. 2016, pp.1-11.
https://search.emarefa.net/detail/BIM-1114475
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114475