Evolving Paradigm of Radiotherapy for High-Risk Prostate Cancer: Current Consensus and Continuing Controversies
Joint Authors
Juloori, Aditya
Shah, Chirag
Stephans, Kevin
Vassil, Andrew
Tendulkar, Rahul
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-23
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
High-risk prostate cancer is an aggressive form of the disease with an increased risk of distant metastasis and subsequent mortality.
Multiple randomized trials have established that the combination of radiation therapy and long-term androgen deprivation therapy improves overall survival compared to either treatment alone.
Standard of care for men with high-risk prostate cancer in the modern setting is dose-escalated radiotherapy along with 2-3 years of androgen deprivation therapy (ADT).
There are research efforts directed towards assessing the efficacy of shorter ADT duration.
Current research has been focused on assessing hypofractionated and stereotactic body radiation therapy (SBRT) techniques.
Ongoing randomized trials will help assess the utility of pelvic lymph node irradiation.
Research is also focused on multimodality therapy with addition of a brachytherapy boost to external beam radiation to help improve outcomes in men with high-risk prostate cancer.
American Psychological Association (APA)
Juloori, Aditya& Shah, Chirag& Stephans, Kevin& Vassil, Andrew& Tendulkar, Rahul. 2016. Evolving Paradigm of Radiotherapy for High-Risk Prostate Cancer: Current Consensus and Continuing Controversies. Prostate Cancer،Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1114888
Modern Language Association (MLA)
Juloori, Aditya…[et al.]. Evolving Paradigm of Radiotherapy for High-Risk Prostate Cancer: Current Consensus and Continuing Controversies. Prostate Cancer No. 2016 (2016), pp.1-12.
https://search.emarefa.net/detail/BIM-1114888
American Medical Association (AMA)
Juloori, Aditya& Shah, Chirag& Stephans, Kevin& Vassil, Andrew& Tendulkar, Rahul. Evolving Paradigm of Radiotherapy for High-Risk Prostate Cancer: Current Consensus and Continuing Controversies. Prostate Cancer. 2016. Vol. 2016, no. 2016, pp.1-12.
https://search.emarefa.net/detail/BIM-1114888
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1114888