Nonmotor Features in Parkinson’s Disease: What Are the Most Important Associated Factors?
Joint Authors
Taba, Pille
Kadastik-Eerme, Liis
Muldmaa, Mari
Lilles, Stella
Rosenthal, Marika
Taba, Nele
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
The purpose of this study was to demonstrate the frequency and severity of nonmotor symptoms and their correlations with a wide range of demographic and clinical factors in a large cohort of patients with Parkinson’s disease (PD).
Methods.
268 PD patients were assessed using the validated Movement Disorders Society’s Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), the Beck Depression Inventory (BDI), Parkinson’s Disease Questionnaire (PDQ-39), the Hoehn and Yahr scale (HY), the Schwab and England Activities of Daily Living (SE-ADL) Scale, and the Minimental State Examination (MMSE).
Results.
Nonmotor symptoms had a strong positive relationship with depression and lower quality of life.
Also, age, duration and severity of PD, cognitive impairment, daily dose, and duration of levodopa treatment correlated with the burden of nonmotor symptoms.
Patients with postural instability and gait disorder (PIGD) dominance or with the presence of motor complications had higher MDS-UPDRS Part I scores expressing the load of nonmotor features, compared to participants with other disease subtypes or without motor complications.
Conclusions.
Though the severity of individual nonmotor symptoms was generally rated by PD patients as “mild” or less, we found a significant cumulative effect of nonmotor symptoms on patients’ mood, daily activities, and quality of life.
American Psychological Association (APA)
Kadastik-Eerme, Liis& Muldmaa, Mari& Lilles, Stella& Rosenthal, Marika& Taba, Nele& Taba, Pille. 2016. Nonmotor Features in Parkinson’s Disease: What Are the Most Important Associated Factors?. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1115236
Modern Language Association (MLA)
Kadastik-Eerme, Liis…[et al.]. Nonmotor Features in Parkinson’s Disease: What Are the Most Important Associated Factors?. Parkinson’s Disease No. 2016 (2016), pp.1-8.
https://search.emarefa.net/detail/BIM-1115236
American Medical Association (AMA)
Kadastik-Eerme, Liis& Muldmaa, Mari& Lilles, Stella& Rosenthal, Marika& Taba, Nele& Taba, Pille. Nonmotor Features in Parkinson’s Disease: What Are the Most Important Associated Factors?. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1115236
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115236