![](/images/graphics-bg.png)
Characteristics of Nonmotor Symptoms in Progressive Supranuclear Palsy
Joint Authors
Song, Wei
Cao, Bei
Shang, Hui-Fang
Wei, Qianqian
Ou, Ruwei
Zhao, Bi
Chen, Ke
Hou, Yanbing
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
To explore the clinical correlates of nonmotor symptoms (NMS) in progressive supranuclear palsy (PSP) and their differences from healthy controls and patients with Parkinson’s disease (PD).
Methods.
Twenty-seven PSP patients, 27 age- and gender-matched healthy controls (HC), and 27 age- and gender-matched PD patients were included for this case-control study.
NMS were assessed using the Nonmotor Symptoms Scale (NMSS, including 9 domains).
Results.
All PSP patients reported NMS.
The frequency and severity of “sleep/fatigue,” “mood/apathy,” “attention/memory,” “gastrointestinal,” “sexual dysfunction,” and “miscellaneous” domains in PSP group were significantly higher than those in HC group ( P < 0.05 ).
The frequency of “mood/apathy,” “attention/memory,” and “sexual dysfunction” domains and the severity of “attention/memory” and “gastrointestinal” domains in PSP group were significantly higher than those in PD group ( P < 0.05 ).
The “attention/memory” domain in PSP had a significant but weak-to-moderate correlation with age ( R = 0.387 , P = 0.046 ) and onset age ( R = 0.406 , P = 0.036 ).
Conclusions.
NMS are common in PSP patients.
Patients with PSP seem to be subjected to more frequent and severe specific NMS compared to healthy aging subjects and PD patients.
Older PSP patients and late-onset patients are likely to be subjected to cognitive decline.
American Psychological Association (APA)
Ou, Ruwei& Song, Wei& Wei, Qianqian& Chen, Ke& Cao, Bei& Hou, Yanbing…[et al.]. 2016. Characteristics of Nonmotor Symptoms in Progressive Supranuclear Palsy. Parkinson’s Disease،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115286
Modern Language Association (MLA)
Ou, Ruwei…[et al.]. Characteristics of Nonmotor Symptoms in Progressive Supranuclear Palsy. Parkinson’s Disease No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1115286
American Medical Association (AMA)
Ou, Ruwei& Song, Wei& Wei, Qianqian& Chen, Ke& Cao, Bei& Hou, Yanbing…[et al.]. Characteristics of Nonmotor Symptoms in Progressive Supranuclear Palsy. Parkinson’s Disease. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115286
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115286