Diagnosis of Peripheral Lung Lesions via Conventional Flexible Bronchoscopy with Multiplanar CT Planning
Joint Authors
Li, Huihua
De Roza, Marianne Anastasia
Quah, Kien Hong
Tay, Cheong Kiat
Toh, Weiquan
Kalyanasundaram, Ganesh
Anantham, Devanand
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-11-13
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Conventional flexible bronchoscopy has limited sensitivity in the diagnosis of peripheral lung lesions and is dependent on lesion size.
However, advancement of CT imaging offers multiplanar reconstruction facilitating enhanced preprocedure planning.
This study aims to report efficacy and safety while considering the impact of patient selection and multiplanar CT planning.
Method.
Prospective case series of patients with peripheral lung lesions suspected of having lung cancer who underwent flexible bronchoscopy (forceps biopsy and lavage).
Endobronchial lesions were excluded.
Patients with negative results underwent CT-guided transthoracic needle aspiration, surgical biopsy, or clinical-radiological surveillance to establish the final diagnosis.
Results.
226 patients were analysed.
The diagnostic yield of bronchoscopy was 80.1% (181/226) with a sensitivity of 84.2% and specificity of 100%.
In patients with a positive CT-Bronchus sign, the diagnostic yield was 82.4% compared to 72.8% with negative CT-Bronchus sign (p=0.116).
Diagnostic yield was 84.9% in lesions > 20 mm and 63.0% in lesions ≤ 20 mm (p=0.001).
Six (2.7%) patients had transient hypoxia and 2 (0.9%) had pneumothorax.
There were no serious adverse events.
Conclusion.
Flexible bronchoscopy with appropriate patient selection and preprocedure planning is more efficacious in obtaining a diagnosis in peripheral lung lesions compared to historical data.
This trial is registered with ClinicalTrials.gov Identifier: NCT01374542.
American Psychological Association (APA)
De Roza, Marianne Anastasia& Quah, Kien Hong& Tay, Cheong Kiat& Toh, Weiquan& Li, Huihua& Kalyanasundaram, Ganesh…[et al.]. 2016. Diagnosis of Peripheral Lung Lesions via Conventional Flexible Bronchoscopy with Multiplanar CT Planning. Pulmonary Medicine،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115296
Modern Language Association (MLA)
De Roza, Marianne Anastasia…[et al.]. Diagnosis of Peripheral Lung Lesions via Conventional Flexible Bronchoscopy with Multiplanar CT Planning. Pulmonary Medicine No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1115296
American Medical Association (AMA)
De Roza, Marianne Anastasia& Quah, Kien Hong& Tay, Cheong Kiat& Toh, Weiquan& Li, Huihua& Kalyanasundaram, Ganesh…[et al.]. Diagnosis of Peripheral Lung Lesions via Conventional Flexible Bronchoscopy with Multiplanar CT Planning. Pulmonary Medicine. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115296
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115296