Peroxisome Proliferator-Activated Receptor Modulation during Metabolic Diseases and Cancers: Master and Minions
Joint Authors
Corrado, F.
D’Anna, Rosario
Vitale, Salvatore Giovanni
Rapisarda, Agnese Maria Chiara
Rossetti, Paola
Buscema, Massimo
Nigro, Angela
La Rosa, Valentina Lucia
Lagana, Antonio Simone
Condorelli, Rosita A.
La Vignera, Sandro
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The prevalence of obesity and metabolic diseases (such as type 2 diabetes mellitus, dyslipidaemia, and cardiovascular diseases) has increased in the last decade, in both industrialized and developing countries.
This also coincided with our observation of a similar increase in the prevalence of cancers.
The aetiology of these diseases is very complex and involves genetic, nutritional, and environmental factors.
Much evidence indicates the central role undertaken by peroxisome proliferator-activated receptors (PPARs) in the development of these disorders.
Due to the fact that their ligands could become crucial in future target-therapies, PPARs have therefore become the focal point of much research.
Based on this evidence, this narrative review was written with the purpose of outlining the effects of PPARs, their actions, and their prospective uses in metabolic diseases and cancers.
American Psychological Association (APA)
Vitale, Salvatore Giovanni& Lagana, Antonio Simone& Nigro, Angela& La Rosa, Valentina Lucia& Rossetti, Paola& Rapisarda, Agnese Maria Chiara…[et al.]. 2016. Peroxisome Proliferator-Activated Receptor Modulation during Metabolic Diseases and Cancers: Master and Minions. PPAR Research،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1115335
Modern Language Association (MLA)
Vitale, Salvatore Giovanni…[et al.]. Peroxisome Proliferator-Activated Receptor Modulation during Metabolic Diseases and Cancers: Master and Minions. PPAR Research No. 2016 (2016), pp.1-9.
https://search.emarefa.net/detail/BIM-1115335
American Medical Association (AMA)
Vitale, Salvatore Giovanni& Lagana, Antonio Simone& Nigro, Angela& La Rosa, Valentina Lucia& Rossetti, Paola& Rapisarda, Agnese Maria Chiara…[et al.]. Peroxisome Proliferator-Activated Receptor Modulation during Metabolic Diseases and Cancers: Master and Minions. PPAR Research. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1115335
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115335