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Analgesic Effect of Dexamethasone after Arthroscopic Knee Surgery: A Randomized Controlled Trial
Joint Authors
Moyano, Jairo
García, Maria
Caicedo, Maria
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Dexamethasone is sometimes used as a coanalgesic because of its anti-inflammatory properties.
Objective.
To evaluate opioid use, postoperative pain intensity, and side effects after a single dose of dexamethasone in patients undergoing arthroscopic knee surgery.
Methods.
In this randomized controlled study patients were randomized to receive either 10 mg of intravenous dexamethasone (DM group) or 0.9% normal saline (NS group) during the intraoperative period.
Primary outcomes were pain intensity and total morphine and codeine use after surgery.
Results.
Seventy-eight patients were included in the study.
The DM group showed statistically significant higher pain intensity at the fourth postoperative hour (DM: 3.96/10, standard deviation [SD] 0.54; NS: 2.46/10, SD 0.45; p=0.036).
No statistically significant difference in total opioid use (morphine plus codeine) was identified with 15.9 (SD 1.97) codeine tablets used in DM group and 20 (SD 2.14) in NS group (p=0.25).
Discussion.
Pain intensity tended to decrease in both groups suggesting morphine as the main source of analgesia.
Conclusions.
Intravenous dexamethasone during the intraoperative period has no clinical impact on postoperative pain intensity during the first 48 h after arthroscopic knee surgery.
This trial is registered with R000020892.
American Psychological Association (APA)
Moyano, Jairo& García, Maria& Caicedo, Maria. 2016. Analgesic Effect of Dexamethasone after Arthroscopic Knee Surgery: A Randomized Controlled Trial. Pain Research and Management،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1115431
Modern Language Association (MLA)
Moyano, Jairo…[et al.]. Analgesic Effect of Dexamethasone after Arthroscopic Knee Surgery: A Randomized Controlled Trial. Pain Research and Management No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1115431
American Medical Association (AMA)
Moyano, Jairo& García, Maria& Caicedo, Maria. Analgesic Effect of Dexamethasone after Arthroscopic Knee Surgery: A Randomized Controlled Trial. Pain Research and Management. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1115431
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115431