Effect of TramadolAcetaminophen on Motivation in Patients with Chronic Low Back Pain
Joint Authors
Ozaki, Toshifumi
Tetsunaga, Tomonori
Tetsunaga, Tomoko
Tanaka, Masato
Takei, Yoshitaka
Nishida, K.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-03-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
The contribution of apathy, frequently recognized in individuals with neurodegenerative diseases, to chronic low back pain (LBP) remains unclear.
Objectives.
To investigate levels of apathy and clinical outcomes in patients with chronic LBP treated with tramadol-acetaminophen.
Methods.
A retrospective case-control study involving 73 patients with chronic LBP (23 male, 50 female; mean age 71 years) treated with tramadol-acetaminophen (n=36) and celecoxib (n=37) was performed.
All patients were assessed using the self-reported questionnaires.
A mediation model was constructed using a bootstrapping method to evaluate the mediating effects of pain relief after treatment.
Results.
A total of 35 (55.6%) patients met the criteria for apathy.
A four-week treatment regimen in the tramadol group conferred significant improvements in the Apathy scale and numerical rating scale but not in the Rolland-Morris Disability Questionnaire, Pain Disability Assessment Scale, or Pain Catastrophizing Scale.
The depression component of the Hospital Anxiety and Depression Scale was lower in the tramadol group than in the celecoxib group.
The mediation analysis found that the impact of tramadol-acetaminophen on the change in apathy was not mediated by the pain relief.
Conclusions.
Tramadol-acetaminophen was effective at reducing chronic LBP and conferred a prophylactic motivational effect in patients with chronic LBP.
American Psychological Association (APA)
Tetsunaga, Tomoko& Tetsunaga, Tomonori& Tanaka, Masato& Nishida, K.& Takei, Yoshitaka& Ozaki, Toshifumi. 2016. Effect of TramadolAcetaminophen on Motivation in Patients with Chronic Low Back Pain. Pain Research and Management،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115496
Modern Language Association (MLA)
Tetsunaga, Tomoko…[et al.]. Effect of TramadolAcetaminophen on Motivation in Patients with Chronic Low Back Pain. Pain Research and Management No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1115496
American Medical Association (AMA)
Tetsunaga, Tomoko& Tetsunaga, Tomonori& Tanaka, Masato& Nishida, K.& Takei, Yoshitaka& Ozaki, Toshifumi. Effect of TramadolAcetaminophen on Motivation in Patients with Chronic Low Back Pain. Pain Research and Management. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115496
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115496