Preoperative Quantitative MR Tractography Compared with Visual Tract Evaluation in Patients with Neuropathologically Confirmed Gliomas Grades II and III: A Prospective Cohort Study
Joint Authors
Latini, Francesco
Delgado, Anna F.
Nilsson, Markus
Mårtensson, Johanna
Zetterling, Maria
Berntsson, Shala G.
Alafuzoff, Irina
Lätt, Jimmy
Larsson, Elna-Marie
Source
Radiology Research and Practice
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-17
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Background and Purpose.
Low-grade gliomas show infiltrative growth in white matter tracts.
Diffusion tensor tractography can noninvasively assess white matter tracts.
The aim was to preoperatively assess tumor growth in white matter tracts using quantitative MR tractography (3T).
The hypothesis was that suspected infiltrated tracts would have altered diffusional properties in infiltrated tract segments compared to noninfiltrated tracts.
Materials and Methods.
Forty-eight patients with suspected low-grade glioma were included after written informed consent and underwent preoperative diffusion tensor imaging in this prospective review-board approved study.
Major white matter tracts in both hemispheres were tracked, segmented, and visually assessed for tumor involvement in thirty-four patients with gliomas grade II or III (astrocytomas or oligodendrogliomas) on postoperative neuropathological evaluation.
Relative fractional anisotropy (rFA) and mean diffusivity (rMD) in tract segments were calculated and compared with visual evaluation and neuropathological diagnosis.
Results.
Tract segment infiltration on visual evaluation was associated with a lower rFA and high rMD in a majority of evaluated tract segments (89% and 78%, resp.).
Grade II and grade III gliomas had similar infiltrating behavior.
Conclusion.
Quantitative MR tractography corresponds to visual evaluation of suspected tract infiltration.
It may be useful for an objective preoperative evaluation of tract segment involvement.
American Psychological Association (APA)
Delgado, Anna F.& Nilsson, Markus& Latini, Francesco& Mårtensson, Johanna& Zetterling, Maria& Berntsson, Shala G.…[et al.]. 2016. Preoperative Quantitative MR Tractography Compared with Visual Tract Evaluation in Patients with Neuropathologically Confirmed Gliomas Grades II and III: A Prospective Cohort Study. Radiology Research and Practice،Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1115701
Modern Language Association (MLA)
Delgado, Anna F.…[et al.]. Preoperative Quantitative MR Tractography Compared with Visual Tract Evaluation in Patients with Neuropathologically Confirmed Gliomas Grades II and III: A Prospective Cohort Study. Radiology Research and Practice No. 2016 (2016), pp.1-15.
https://search.emarefa.net/detail/BIM-1115701
American Medical Association (AMA)
Delgado, Anna F.& Nilsson, Markus& Latini, Francesco& Mårtensson, Johanna& Zetterling, Maria& Berntsson, Shala G.…[et al.]. Preoperative Quantitative MR Tractography Compared with Visual Tract Evaluation in Patients with Neuropathologically Confirmed Gliomas Grades II and III: A Prospective Cohort Study. Radiology Research and Practice. 2016. Vol. 2016, no. 2016, pp.1-15.
https://search.emarefa.net/detail/BIM-1115701
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115701