Molecular Targets and Emerging Therapeutic Options for Uterine Leiomyosarcoma
Joint Authors
Miller, Heather
Ike, Chiemeka
Parma, Jennifer
Masand, Ramya P.
Mach, Claire M.
Anderson, Matthew L.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-09-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Uterine leiomyosarcoma (uLMS) is an aggressive malignancy characterized by its early metastasis, high rates of recurrence, and poor prognosis.
Multiple obstacles complicate the clinical management of uLMS.
These include the fact that most uLMS are typically identified only after a woman has undergone hysterectomy or myomectomy, the limited efficacy of adjuvant therapy for early stage disease, and the poor response of metastatic disease to current treatments.
Here, we discuss recent insights into the molecular basis of uLMS and discuss emerging options for its clinical management.
Particular attention is given to the biologic basis of these strategies with the goal of understanding the rationale motivating their use.
American Psychological Association (APA)
Miller, Heather& Ike, Chiemeka& Parma, Jennifer& Masand, Ramya P.& Mach, Claire M.& Anderson, Matthew L.. 2016. Molecular Targets and Emerging Therapeutic Options for Uterine Leiomyosarcoma. Complexity،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115782
Modern Language Association (MLA)
Miller, Heather…[et al.]. Molecular Targets and Emerging Therapeutic Options for Uterine Leiomyosarcoma. Complexity No. 2016 (2016), pp.1-7.
https://search.emarefa.net/detail/BIM-1115782
American Medical Association (AMA)
Miller, Heather& Ike, Chiemeka& Parma, Jennifer& Masand, Ramya P.& Mach, Claire M.& Anderson, Matthew L.. Molecular Targets and Emerging Therapeutic Options for Uterine Leiomyosarcoma. Complexity. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1115782
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1115782