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A Role for Notch Signalling in Breast Cancer and Endocrine Resistance
Joint Authors
Acar, Ahmet
Simões, Bruno M.
Clarke, Robert B.
Brennan, Keith
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-10
Country of Publication
Egypt
No. of Pages
6
Abstract EN
Over the past decade, there has been growing interest in the Notch signalling pathway within the breast cancer field.
This interest stemmed initially from the observation that Notch signalling is aberrantly activated in breast cancer and its effects on various cellular processes including proliferation, apoptosis, and cancer stem cell activity.
However more recently, elevated Notch signalling has been correlated with therapy resistance in oestrogen receptor-positive breast cancer.
As a result, inhibiting Notch signalling with therapeutic agents is being explored as a promising treatment option for breast cancer patients.
American Psychological Association (APA)
Acar, Ahmet& Simões, Bruno M.& Clarke, Robert B.& Brennan, Keith. 2016. A Role for Notch Signalling in Breast Cancer and Endocrine Resistance. Stem Cells International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1116231
Modern Language Association (MLA)
Acar, Ahmet…[et al.]. A Role for Notch Signalling in Breast Cancer and Endocrine Resistance. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1116231
American Medical Association (AMA)
Acar, Ahmet& Simões, Bruno M.& Clarke, Robert B.& Brennan, Keith. A Role for Notch Signalling in Breast Cancer and Endocrine Resistance. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1116231
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1116231