Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells
Joint Authors
Rizvanov, Albert A.
Bissoyi, Akalabya
Gusev, Oleg A.
Kumar, Awanish
Nesmelov, Alexander
Patra, Pradeep Kumar
Bit, Arindam
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-08-14
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Mesenchymal Stem Cells (MSCs) are a promising mammalian cell type as they can be used for the reconstruction of human tissues and organs.
MSCs are shown to form bone, cartilage, fat, and muscle-like cells under specific cultivation conditions.
Current technology of MSCs cryopreservation has significant disadvantages.
Alternative technologies of mammalian cells preservation through lyophilisation or desiccation (air-drying) are among the upcoming domains of investigation in the field of cryobiology.
Different protectants and their combinations were studied in this context.
Loading of the protectant in the live cell can be a challenging issue but recent studies have shown encouraging results.
This paper deals with a review of the protectants, methods of their delivery, and physical boundary conditions adopted for the desiccation and lyophilisation of mammalian cells, including MSCs.
A hybrid technique combining both methods is also proposed as a promising way of MSCs dry preservation.
American Psychological Association (APA)
Bissoyi, Akalabya& Kumar, Awanish& Rizvanov, Albert A.& Nesmelov, Alexander& Gusev, Oleg A.& Patra, Pradeep Kumar…[et al.]. 2016. Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells. Stem Cells International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1116406
Modern Language Association (MLA)
Bissoyi, Akalabya…[et al.]. Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1116406
American Medical Association (AMA)
Bissoyi, Akalabya& Kumar, Awanish& Rizvanov, Albert A.& Nesmelov, Alexander& Gusev, Oleg A.& Patra, Pradeep Kumar…[et al.]. Recent Advances and Future Direction in Lyophilisation and Desiccation of Mesenchymal Stem Cells. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1116406
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1116406