Molecular Imaging of Stem Cell Transplantation for Liver Diseases: Monitoring, Clinical Translation, and Theranostics
Joint Authors
Rizzo, S.
Petrella, Francesco
Nicosia, Luca
Wang, Ping
Bellomi, Massimo
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-12-14
Country of Publication
Egypt
No. of Pages
8
Abstract EN
Stem cell transplantation has been investigated to rescue experimental liver failure and is promising to offer an alternative therapy to liver transplantation for liver diseases treatment.
Several clinical studies in this field have been carried out, but the therapeutic benefit of this treatment is still controversial.
A major obstacle to developing stem cell therapies in clinic is being able to visualize the cells in vivo.
Imaging modalities allow optimization of delivery, detecting cell survival and functionality by in vivo monitoring these transplanted graft cells.
Moreover, theranostic imaging is a brand new field that utilizes nanometer-scale materials to glean diagnostic insight for simultaneous treatment, which is very promising to improve stem cell-based therapy for treatment of liver diseases.
The aim of this review was to summarize the various imaging tools that have been explored with advanced molecular imaging probes.
We also outline some recent progress of preclinical and clinical studies of liver stem cells transplantation.
Finally, we discuss theranostic imaging for stem cells transplantation for liver dysfunction and future opportunities afforded by theranostic imaging.
American Psychological Association (APA)
Wang, Ping& Petrella, Francesco& Nicosia, Luca& Bellomi, Massimo& Rizzo, S.. 2016. Molecular Imaging of Stem Cell Transplantation for Liver Diseases: Monitoring, Clinical Translation, and Theranostics. Stem Cells International،Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1116483
Modern Language Association (MLA)
Wang, Ping…[et al.]. Molecular Imaging of Stem Cell Transplantation for Liver Diseases: Monitoring, Clinical Translation, and Theranostics. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-8.
https://search.emarefa.net/detail/BIM-1116483
American Medical Association (AMA)
Wang, Ping& Petrella, Francesco& Nicosia, Luca& Bellomi, Massimo& Rizzo, S.. Molecular Imaging of Stem Cell Transplantation for Liver Diseases: Monitoring, Clinical Translation, and Theranostics. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-8.
https://search.emarefa.net/detail/BIM-1116483
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1116483