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Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases
Joint Authors
Lee, Min-Young
Lee, Chang Youn
Kim, Ran
Ham, Onju
Lee, Jihyun
Kim, Pilseog
Lee, Seokyeon
Oh, Sekyung
Lee, Hojin
Kim, Jongmin
Chang, Woochul
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-10-18
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Despite development of medicine, cardiovascular diseases (CVDs) are still the leading cause of mortality and morbidity worldwide.
Over the past 10 years, various stem cells have been utilized in therapeutic strategies for the treatment of CVDs.
CVDs are characterized by a broad range of pathological reactions including inflammation, necrosis, hyperplasia, and hypertrophy.
However, the causes of CVDs are still unclear.
While there is a limit to the currently available target-dependent treatments, the therapeutic potential of stem cells is very attractive for the treatment of CVDs because of their paracrine effects, anti-inflammatory activity, and immunomodulatory capacity.
Various studies have recently reported increased therapeutic potential of transplantation of microRNA- (miRNA-) overexpressing stem cells or small-molecule-treated cells.
In addition to treatment with drugs or overexpressed miRNA in stem cells, stem cell-derived extracellular vesicles also have therapeutic potential because they can deliver the stem cell-specific RNA and protein into the host cell, thereby improving cell viability.
Here, we reported the state of stem cell-based therapy for the treatment of CVDs and the potential for cell-free based therapy.
American Psychological Association (APA)
Lee, Chang Youn& Kim, Ran& Ham, Onju& Lee, Jihyun& Kim, Pilseog& Lee, Seokyeon…[et al.]. 2016. Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases. Stem Cells International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1116531
Modern Language Association (MLA)
Lee, Chang Youn…[et al.]. Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1116531
American Medical Association (AMA)
Lee, Chang Youn& Kim, Ran& Ham, Onju& Lee, Jihyun& Kim, Pilseog& Lee, Seokyeon…[et al.]. Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1116531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1116531