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Genetic Engineering of Mesenchymal Stem Cells to Induce Their Migration and Survival
Joint Authors
Nowakowski, Adam
Walczak, Piotr
Lukomska, Barbara
Janowski, Miroslaw
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-05-03
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Mesenchymal stem cells (MSCs) are very attractive for regenerative medicine due to their relatively easy derivation and broad range of differentiation capabilities, either naturally or induced through cell engineering.
However, efficient methods of delivery to diseased tissues and the long-term survival of grafted cells still need improvement.
Here, we review genetic engineering approaches designed to enhance the migratory capacities of MSCs, as well as extend their survival after transplantation by the modulation of prosurvival approaches, including prevention of senescence and apoptosis.
We highlight some of the latest examples that explore these pivotal points, which have great relevance in cell-based therapies.
American Psychological Association (APA)
Nowakowski, Adam& Walczak, Piotr& Lukomska, Barbara& Janowski, Miroslaw. 2016. Genetic Engineering of Mesenchymal Stem Cells to Induce Their Migration and Survival. Stem Cells International،Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1116676
Modern Language Association (MLA)
Nowakowski, Adam…[et al.]. Genetic Engineering of Mesenchymal Stem Cells to Induce Their Migration and Survival. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-9.
https://search.emarefa.net/detail/BIM-1116676
American Medical Association (AMA)
Nowakowski, Adam& Walczak, Piotr& Lukomska, Barbara& Janowski, Miroslaw. Genetic Engineering of Mesenchymal Stem Cells to Induce Their Migration and Survival. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-9.
https://search.emarefa.net/detail/BIM-1116676
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1116676