Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics
Joint Authors
Fulzele, Sadanand
Kolhe, Ravindra
Burke, John
Hunter, Monte
Isales, Carlos
Hamrick, Mark
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-01-19
Country of Publication
Egypt
No. of Pages
6
Abstract EN
Within the field of regenerative medicine, many have sought to use stem cells as a promising way to heal human tissue; however, in the past few years, exosomes (packaged vesicles released from cells) have shown more exciting promise.
Specifically, stem cell-derived exosomes have demonstrated great ability to provide therapeutical benefits.
Exosomal products can include miRNA, other genetic products, proteins, and various factors.
They are released from cells in a paracrine fashion in order to combat local cellular stress.
Because of this, there are vast benefits that medicine can obtain from stem cell-derived exosomes.
If exosomes could be extracted from stem cells in an efficient manner and packaged with particular regenerative products, then diseases such as rheumatoid arthritis, osteoarthritis, bone fractures, and other maladies could be treated with cell-free regenerative medicine via exosomes.
Many advances must be made to get to this point, and the following review highlights the current advances of stem cell-derived exosomes with particular attention to regenerative medicine in orthopaedics.
American Psychological Association (APA)
Burke, John& Kolhe, Ravindra& Hunter, Monte& Isales, Carlos& Hamrick, Mark& Fulzele, Sadanand. 2016. Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics. Stem Cells International،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1116834
Modern Language Association (MLA)
Burke, John…[et al.]. Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-6.
https://search.emarefa.net/detail/BIM-1116834
American Medical Association (AMA)
Burke, John& Kolhe, Ravindra& Hunter, Monte& Isales, Carlos& Hamrick, Mark& Fulzele, Sadanand. Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1116834
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1116834