Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins
Joint Authors
Nakamura, Masaya
Fukusumi, Hayato
Shofuda, Tomoko
Bamba, Yohei
Yamamoto, Atsuyo
Kanematsu, Daisuke
Handa, Yukako
Okita, Keisuke
Yamanaka, Shinya
Kanemura, Yonehiro
Okano, Hideyuki
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-26
Country of Publication
Egypt
No. of Pages
10
Abstract EN
Human neural progenitor cells (hNPCs) have previously been generated from limited numbers of human induced pluripotent stem cell (hiPSC) clones.
Here, 21 hiPSC clones derived from human dermal fibroblasts, cord blood cells, and peripheral blood mononuclear cells were differentiated using two neural induction methods, an embryoid body (EB) formation-based method and an EB formation method using dual SMAD inhibitors (dSMADi).
Our results showed that expandable hNPCs could be generated from hiPSC clones with diverse somatic tissue origins.
The established hNPCs exhibited a mid/hindbrain-type neural identity and uniform expression of neural progenitor genes.
American Psychological Association (APA)
Fukusumi, Hayato& Shofuda, Tomoko& Bamba, Yohei& Yamamoto, Atsuyo& Kanematsu, Daisuke& Handa, Yukako…[et al.]. 2016. Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins. Stem Cells International،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1117083
Modern Language Association (MLA)
Fukusumi, Hayato…[et al.]. Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-10.
https://search.emarefa.net/detail/BIM-1117083
American Medical Association (AMA)
Fukusumi, Hayato& Shofuda, Tomoko& Bamba, Yohei& Yamamoto, Atsuyo& Kanematsu, Daisuke& Handa, Yukako…[et al.]. Establishment of Human Neural Progenitor Cells from Human Induced Pluripotent Stem Cells with Diverse Tissue Origins. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1117083
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117083