Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair
Joint Authors
Rahim, Ahad A.
Bhangra, Kulraj Singh
Busuttil, Francesca
Phillips, James B.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-18, 18 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-26
Country of Publication
Egypt
No. of Pages
18
Abstract EN
Peripheral nerve injury continues to pose a clinical hurdle despite its frequency and advances in treatment.
Unlike the central nervous system, neurons of the peripheral nervous system have a greater ability to regenerate.
However, due to a number of confounding factors, this is often both incomplete and inadequate.
The lack of supportive Schwann cells or their inability to maintain a regenerative phenotype is a major factor.
Advances in nervous system tissue engineering technology have led to efforts to build Schwann cell scaffolds to overcome this and enhance the regenerative capacity of neurons following injury.
Stem cells that can differentiate along a neural lineage represent an essential resource and starting material for this process.
In this review, we discuss the different stem cell types that are showing promise for nervous system tissue engineering in the context of peripheral nerve injury.
We also discuss some of the biological, practical, ethical, and commercial considerations in using these different stem cells for future clinical application.
American Psychological Association (APA)
Bhangra, Kulraj Singh& Busuttil, Francesca& Phillips, James B.& Rahim, Ahad A.. 2016. Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair. Stem Cells International،Vol. 2016, no. 2016, pp.1-18.
https://search.emarefa.net/detail/BIM-1117116
Modern Language Association (MLA)
Bhangra, Kulraj Singh…[et al.]. Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-18.
https://search.emarefa.net/detail/BIM-1117116
American Medical Association (AMA)
Bhangra, Kulraj Singh& Busuttil, Francesca& Phillips, James B.& Rahim, Ahad A.. Using Stem Cells to Grow Artificial Tissue for Peripheral Nerve Repair. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-18.
https://search.emarefa.net/detail/BIM-1117116
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117116