Influence of Blood Vessels on Temperature during High-Intensity Focused Ultrasound Hyperthermia Based on the Thermal Wave Model of Bioheat Transfer
Joint Authors
Tan, Qiaolai
Zou, Xiao
Dong, Hu
Ding, Yajun
Zhao, Xinmin
Source
Advances in Condensed Matter Physics
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-09-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The coupled effects of blood vessels and thermal relaxation time on temperature and thermal lesion region in biological tissue during high-intensity focused ultrasound (HIFU) hyperthermia are numerically investigated.
Considering the non-Fourier behavior of heat conduction in biological tissue, the traditional Pennes bioheat equation was modified to thermal wave model of bioheat transfer (TWMBT).
Consequently, a joint physical model, which combines TWMBT for tissue and energy transport equation for blood vessel, is presented to predict the evolution of temperature and the thermal lesion region.
In this study, pulsatile blood flow is first introduced into numerical study of HIFU hyperthermia, and thermal relaxation time, ultrasonic focus location, blood vessel radius, and blood flow velocity are all taken into account.
The results show that the thermal relaxation time plays a key role in the temperature and the thermal lesion region.
Larger thermal relaxation time results in lower temperature and smaller thermal lesion region, which indicates that TWMBT leads to lower temperature and smaller thermal lesion region compared to Pennes bioheat transfer model.
In addition, we found that the ultrasonic focus location and blood vessel radius significantly affected the temperature and thermal lesion region, while the heartbeat frequency and amplitude factor of pulsating blood flow as well as the average velocity of blood flow had only a slight effect.
American Psychological Association (APA)
Tan, Qiaolai& Zou, Xiao& Dong, Hu& Ding, Yajun& Zhao, Xinmin. 2018. Influence of Blood Vessels on Temperature during High-Intensity Focused Ultrasound Hyperthermia Based on the Thermal Wave Model of Bioheat Transfer. Advances in Condensed Matter Physics،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1117234
Modern Language Association (MLA)
Tan, Qiaolai…[et al.]. Influence of Blood Vessels on Temperature during High-Intensity Focused Ultrasound Hyperthermia Based on the Thermal Wave Model of Bioheat Transfer. Advances in Condensed Matter Physics No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1117234
American Medical Association (AMA)
Tan, Qiaolai& Zou, Xiao& Dong, Hu& Ding, Yajun& Zhao, Xinmin. Influence of Blood Vessels on Temperature during High-Intensity Focused Ultrasound Hyperthermia Based on the Thermal Wave Model of Bioheat Transfer. Advances in Condensed Matter Physics. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1117234
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117234