The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells

Joint Authors

Izzo, Francesco
Bimonte, Sabrina
Barbieri, Antonio
Amore, Alfonso
del Vecchio, Vitale
Falco, Michela
Leongito, Maddalena
Palaia, Raffaele
Palma, Giuseppe
Piccirillo, Mauro
Granata, Vincenza
Albino, Vittorio
Petrillo, Antonella

Source

Stem Cells International

Issue

Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2016-02-24

Country of Publication

Egypt

No. of Pages

7

Abstract EN

Pancreatic ductal adenocarcinoma is currently one of the deadliest cancers with low overall survival rate.

This disease leads to an aggressive local invasion and early metastases and is poorly responsive to treatment with chemotherapy or chemoradiotherapy.

Several studies have shown that pancreatic cancer stem cells (PCSCs) play different roles in the regulation of drug resistance and recurrence in pancreatic cancer.

MicroRNA (miRNA), a class of newly emerging small noncoding RNAs, is involved in the modulation of several biological activities ranging from invasion to metastases development, as well as drug resistance of pancreatic cancer.

In this review, we synthesize the latest findings on the role of miRNAs in regulating different biological properties of pancreatic cancer stem cells.

American Psychological Association (APA)

Barbieri, Antonio& Leongito, Maddalena& Palma, Giuseppe& del Vecchio, Vitale& Falco, Michela& Palaia, Raffaele…[et al.]. 2016. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells. Stem Cells International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1117249

Modern Language Association (MLA)

Barbieri, Antonio…[et al.]. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1117249

American Medical Association (AMA)

Barbieri, Antonio& Leongito, Maddalena& Palma, Giuseppe& del Vecchio, Vitale& Falco, Michela& Palaia, Raffaele…[et al.]. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1117249

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1117249