The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells
Joint Authors
Izzo, Francesco
Bimonte, Sabrina
Barbieri, Antonio
Amore, Alfonso
del Vecchio, Vitale
Falco, Michela
Leongito, Maddalena
Palaia, Raffaele
Palma, Giuseppe
Piccirillo, Mauro
Granata, Vincenza
Albino, Vittorio
Petrillo, Antonella
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2015), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-02-24
Country of Publication
Egypt
No. of Pages
7
Abstract EN
Pancreatic ductal adenocarcinoma is currently one of the deadliest cancers with low overall survival rate.
This disease leads to an aggressive local invasion and early metastases and is poorly responsive to treatment with chemotherapy or chemoradiotherapy.
Several studies have shown that pancreatic cancer stem cells (PCSCs) play different roles in the regulation of drug resistance and recurrence in pancreatic cancer.
MicroRNA (miRNA), a class of newly emerging small noncoding RNAs, is involved in the modulation of several biological activities ranging from invasion to metastases development, as well as drug resistance of pancreatic cancer.
In this review, we synthesize the latest findings on the role of miRNAs in regulating different biological properties of pancreatic cancer stem cells.
American Psychological Association (APA)
Barbieri, Antonio& Leongito, Maddalena& Palma, Giuseppe& del Vecchio, Vitale& Falco, Michela& Palaia, Raffaele…[et al.]. 2016. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells. Stem Cells International،Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1117249
Modern Language Association (MLA)
Barbieri, Antonio…[et al.]. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells. Stem Cells International Vol. 2016, no. 2016 (2015), pp.1-7.
https://search.emarefa.net/detail/BIM-1117249
American Medical Association (AMA)
Barbieri, Antonio& Leongito, Maddalena& Palma, Giuseppe& del Vecchio, Vitale& Falco, Michela& Palaia, Raffaele…[et al.]. The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells. Stem Cells International. 2016. Vol. 2016, no. 2016, pp.1-7.
https://search.emarefa.net/detail/BIM-1117249
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117249