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RNA Detection Based on Graphene Field-Effect Transistor Biosensor
Joint Authors
Xu, Shicai
Tian, Meng
Zhang, Junye
Wang, Xiaoxin
Li, Zhenhua
Liu, Huilan
Song, Ruihong
Yu, Ziheng
Wang, Jihua
Source
Advances in Condensed Matter Physics
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-06-03
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Graphene has attracted much attention in biosensing applications due to its unique properties.
In this paper, the monolayer graphene was grown by chemical vapor deposition (CVD) method.
Using the graphene as the electric channel, we have fabricated a graphene field-effect transistor (G-FET) biosensor that can be used for label-free detection of RNA.
Compared with conventional method, the G-FET RNA biosensor can be run in low cost, be time-saving, and be miniaturized for RNA measurement.
The sensors show high performance and achieve the RNA detection sensitivity as low as 0.1 fM, which is two orders of magnitude lower than the previously reports.
Moreover, the G-FET biosensor can readily distinguish target RNA from noncomplementary RNA, showing high selectivity for RNA detection.
The developed G-FET RNA biosensor with high sensitivity, fast analysis speed, and simple operation may provide a new feasible direction for RNA research and biosensing.
American Psychological Association (APA)
Tian, Meng& Xu, Shicai& Zhang, Junye& Wang, Xiaoxin& Li, Zhenhua& Liu, Huilan…[et al.]. 2018. RNA Detection Based on Graphene Field-Effect Transistor Biosensor. Advances in Condensed Matter Physics،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1117325
Modern Language Association (MLA)
Tian, Meng…[et al.]. RNA Detection Based on Graphene Field-Effect Transistor Biosensor. Advances in Condensed Matter Physics No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1117325
American Medical Association (AMA)
Tian, Meng& Xu, Shicai& Zhang, Junye& Wang, Xiaoxin& Li, Zhenhua& Liu, Huilan…[et al.]. RNA Detection Based on Graphene Field-Effect Transistor Biosensor. Advances in Condensed Matter Physics. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1117325
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117325