Phytochemical Screening and Biological Activity of Mentha × piperita L. and Lavandula angustifolia Mill. Extracts
Joint Authors
Danciu, Corina
Dehelean, Cristina
Alexa, Ersilia
Radulov, Isidora
Obistioiu, Diana
Sumalan, Renata Maria
Morar, Adriana
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The present study aimed to investigate the phytochemical composition of Mentha × piperita L.
(MP) and Lavandula angustifolia Mill.
(LA) extracts in terms of hydroxycinnamic acid (HCAs) content, in particular, caffeic (CA), p-cumaric (CU), ferulic (FE), and rosmarinic (RS) acids using LC-MS.
Also, the in vitro antimicrobial effect against Staphylococcus aureus and the antiproliferative activity against two cancerous cell lines (A375 and MDA-MB-231) using the MTT assay were tested.
The extracts were prepared using aromatic water which resulted from the extraction of oils from plants as extraction medium, with/without acid.
The results showed that RS and FE represent the majority of HCAs compounds; the highest content of FE is found in LA (7.47 mg·g–1d.m.), and the maximum content of RS in MP (6.36 mg·g–1d.m.).
Regarding the antimicrobial effect against Staphylococcus aureus, the two extracts showed a simulative role on the growth rate of Staphyloccocus aureus, but a slightly inhibitory effect (69.12%) can be attributed to the acidic environment.
In terms of biological activity against MDA-MB-231 breast carcinoma cell line, and A375 human melanoma cell line, at the highest employed concentration, 150 μg·mL–1, the tested extracts present a weak antiproliferative effect.
American Psychological Association (APA)
Alexa, Ersilia& Danciu, Corina& Radulov, Isidora& Obistioiu, Diana& Sumalan, Renata Maria& Morar, Adriana…[et al.]. 2018. Phytochemical Screening and Biological Activity of Mentha × piperita L. and Lavandula angustifolia Mill. Extracts. Analytical Cellular Pathology،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1117437
Modern Language Association (MLA)
Alexa, Ersilia…[et al.]. Phytochemical Screening and Biological Activity of Mentha × piperita L. and Lavandula angustifolia Mill. Extracts. Analytical Cellular Pathology No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1117437
American Medical Association (AMA)
Alexa, Ersilia& Danciu, Corina& Radulov, Isidora& Obistioiu, Diana& Sumalan, Renata Maria& Morar, Adriana…[et al.]. Phytochemical Screening and Biological Activity of Mentha × piperita L. and Lavandula angustifolia Mill. Extracts. Analytical Cellular Pathology. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1117437
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117437