Analysis and Enhancements of a Prolific Macroscopic Model of Epilepsy
Joint Authors
Fietkiewicz, Christopher
Loparo, Kenneth A.
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-07
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Macroscopic models of epilepsy can deliver surprisingly realistic EEG simulations.
In the present study, a prolific series of models is evaluated with regard to theoretical and computational concerns, and enhancements are developed.
Specifically, we analyze three aspects of the models: (1) Using dynamical systems analysis, we demonstrate and explain the presence of direct current potentials in the simulated EEG that were previously undocumented.
(2) We explain how the system was not ideally formulated for numerical integration of stochastic differential equations.
A reformulated system is developed to support proper methodology.
(3) We explain an unreported contradiction in the published model specification regarding the use of a mathematical reduction method.
We then use the method to reduce the number of equations and further improve the computational efficiency.
The intent of our critique is to enhance the evolution of macroscopic modeling of epilepsy and assist others who wish to explore this exciting class of models further.
American Psychological Association (APA)
Fietkiewicz, Christopher& Loparo, Kenneth A.. 2016. Analysis and Enhancements of a Prolific Macroscopic Model of Epilepsy. Scientifica،Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1117630
Modern Language Association (MLA)
Fietkiewicz, Christopher& Loparo, Kenneth A.. Analysis and Enhancements of a Prolific Macroscopic Model of Epilepsy. Scientifica No. 2016 (2016), pp.1-10.
https://search.emarefa.net/detail/BIM-1117630
American Medical Association (AMA)
Fietkiewicz, Christopher& Loparo, Kenneth A.. Analysis and Enhancements of a Prolific Macroscopic Model of Epilepsy. Scientifica. 2016. Vol. 2016, no. 2016, pp.1-10.
https://search.emarefa.net/detail/BIM-1117630
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117630