Formulation Design and Development of a Unani Transdermal Patch for Antiemetic Therapy and Its Pharmaceutical Evaluation
Joint Authors
Saleem, Mohd Nauman
Idris, Mohammad
Source
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-06-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
The Transdermal Drug Delivery System (TDDS) is one of the novel routes for systemic delivery of drugs through intact skin.
A transdermal patch (TP) is a medicated patch that is placed on skin for delivery of medication through skin into the blood stream.
The aim of present study was to formulate and evaluate a Unani transdermal patch that could be used for antiemetic therapy.
The incorporation of Unani ingredients, namely, Khardal (Brassica nigra), Zanjabeel (Zingiber officinale), Podina (Mentha arvensis), and Sirka (Vinegar) were envisaged.
The TP was prepared by solvent evaporation technique and was evaluated for organoleptic characteristics and other physicochemical properties, such as thickness, weight uniformity, folding endurance, moisture content, drug content, and tolerability and acceptability of patch.
The in vitro permeation study of the patch was carried out through Franz diffusion cell using egg shell membrane as barrier membrane.
Phosphate buffer pH 7.4 was used as dissolution medium and the temperature was maintained at 37 ± 1°C.
The in vitro permeation study of the prepared TP indicated a time dependent increase in drug release throughout the study.
The percentage of cumulative drug release was found to be 77.38% in 24 hours.
The study shows a new approach to work in Unani pharmaceutics.
American Psychological Association (APA)
Saleem, Mohd Nauman& Idris, Mohammad. 2016. Formulation Design and Development of a Unani Transdermal Patch for Antiemetic Therapy and Its Pharmaceutical Evaluation. Scientifica،Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1117886
Modern Language Association (MLA)
Saleem, Mohd Nauman& Idris, Mohammad. Formulation Design and Development of a Unani Transdermal Patch for Antiemetic Therapy and Its Pharmaceutical Evaluation. Scientifica No. 2016 (2016), pp.1-5.
https://search.emarefa.net/detail/BIM-1117886
American Medical Association (AMA)
Saleem, Mohd Nauman& Idris, Mohammad. Formulation Design and Development of a Unani Transdermal Patch for Antiemetic Therapy and Its Pharmaceutical Evaluation. Scientifica. 2016. Vol. 2016, no. 2016, pp.1-5.
https://search.emarefa.net/detail/BIM-1117886
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1117886