Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group
Joint Authors
Alvarez-Roman, M. Teresa
Mingot-Castellano, María Eva
Fernández Fuertes, Luis Fernando
González-López, Tomás José
Guinea de Castro, José María
Jarque, Isidro
López-Fernández, M. Fernanda
Lozano, Maria Luisa
Sánchez González, Blanca
Ferreiras, David Valcárcel
González Porras, José Ramón
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-22
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background and Objective.
Diagnosis and management of primary immune thrombocytopenia (ITP) have changed dramatically in the last decade.
The aim of the study was to obtain information about the opinion of the Spanish ITP Group (GEPTI) members regarding the best clinical practices for diagnosis and management of adult patients with ITP.
Materials and Methods.
A two-round Delphi method was carried out by sending to 129 experts a 90-item questionnaire developed by 11 specialists, with a 4-point Likert scale (“never,” “sometimes,” “frequently,” and “always”) for the assessment of responses.
Results.
Forty out of the 129 experts participated in the survey (participation rate 30.2%) and 39 completed the questionnaire (response rate 97.5%).
Salient consensus points included the following: the need to indicate workup studies from a sustained platelet count < 100 x 109/L in the absence of a clear etiology; bone marrow aspiration in elderly patients with suspected ITP; beginning treatment in asymptomatic patients with a platelet count < 20 x 109/L; not exceeding 6-7 weeks of corticosteroid therapy; switching from corticosteroids to one thrombopoietin receptor agonist (TRA); switching to other TRA or other options as combinations of them with immunosuppressive drugs in case of failure; how to reduce tapering TRA; treating patients with symptomatic persistent ITP and platelet count > 20 x 109/L; and considering mucosal or severe bleeding as a basic criterion for hospital admission.
Conclusions.
The present consensus document provides a reference framework for the management of patients with ITP in clinical practice.
American Psychological Association (APA)
Mingot-Castellano, María Eva& Alvarez-Roman, M. Teresa& Fernández Fuertes, Luis Fernando& González-López, Tomás José& Guinea de Castro, José María& Jarque, Isidro…[et al.]. 2019. Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group. Advances in Hematology،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1118093
Modern Language Association (MLA)
Mingot-Castellano, María Eva…[et al.]. Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group. Advances in Hematology No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1118093
American Medical Association (AMA)
Mingot-Castellano, María Eva& Alvarez-Roman, M. Teresa& Fernández Fuertes, Luis Fernando& González-López, Tomás José& Guinea de Castro, José María& Jarque, Isidro…[et al.]. Management of Adult Patients with Primary Immune Thrombocytopenia (ITP) in Clinical Practice: A Consensus Approach of the Spanish ITP Expert Group. Advances in Hematology. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1118093
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1118093