Research on Human Erythrocyte’s Threshold Free Energy for Hemolysis and Damage from Coupling Effect of Shear and Impact Based on Immersed Boundary-Lattice Boltzmann Method
Joint Authors
Wang, Liang
Yun, Zhong
Xiang, Chuang
Source
Applied Bionics and Biomechanics
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-02
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Researches on the principle of human red blood cell’s (RBC) injuring and judgment basis play an important role in decreasing the hemolysis in a blood pump.
In the current study, the judgment of hemolysis in a blood pump study was through some experiment data and empirical formula.
The paper forms a criterion of RBC’s mechanical injury in the aspect of RBC’s free energy.
First, the paper introduces the nonlinear spring network model of RBC in the frame of immersed boundary-lattice Boltzmann method (IB-LBM).
Then, the shape, free energy, and time needed for erythrocyte to be shorn in different shear flow and impacted in different impact flow are simulated.
Combining existing research on RBC’s threshold limit for hemolysis in shear and impact flow with this paper’s, the RBC’s free energy of the threshold limit for hemolysis is found to be 3.46×10−15 J.
The threshold impact velocity of RBC for hemolysis is 8.68 m/s.
The threshold value of RBC can be used for judgment of RBC’s damage when the RBC is having a complicated flow of blood pumps such as coupling effect of shear and impact flow.
According to the change law of RBC’s free energy in the process of being shorn and impacted, this paper proposed a judging criterion for hemolysis when the RBC is under the coupling effect of shear and impact based on the increased free energy of RBC.
American Psychological Association (APA)
Yun, Zhong& Xiang, Chuang& Wang, Liang. 2020. Research on Human Erythrocyte’s Threshold Free Energy for Hemolysis and Damage from Coupling Effect of Shear and Impact Based on Immersed Boundary-Lattice Boltzmann Method. Applied Bionics and Biomechanics،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1120223
Modern Language Association (MLA)
Yun, Zhong…[et al.]. Research on Human Erythrocyte’s Threshold Free Energy for Hemolysis and Damage from Coupling Effect of Shear and Impact Based on Immersed Boundary-Lattice Boltzmann Method. Applied Bionics and Biomechanics No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1120223
American Medical Association (AMA)
Yun, Zhong& Xiang, Chuang& Wang, Liang. Research on Human Erythrocyte’s Threshold Free Energy for Hemolysis and Damage from Coupling Effect of Shear and Impact Based on Immersed Boundary-Lattice Boltzmann Method. Applied Bionics and Biomechanics. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1120223
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1120223