Treatment Outcome and Associated Factors among Tuberculosis Patients in Debre Tabor, Northwestern Ethiopia: A Retrospective Study

Abstract EN

Background.

Assessing the outcomes of tuberculosis (TB) treatment is an important indicator for evaluation of the effectiveness of tuberculosis control programs.

In Ethiopia, directly observed treatment short course (DOTS) was included in the national tuberculosis control program as a strategy but little is known about its effectiveness in the study area.

Therefore, this study was aimed at assessing the treatment outcomes of TB patients and associated factors in Debre Tabor, northwest Ethiopia.

Methods.

A retrospective study was conducted among TB patients for the period from May 2008 to April 2013 at Debre Tabor Health Center, northwest Ethiopia.

Data were entered and analyzed using SPSS version 20.0.

Descriptive statistics were used to generate frequency tables and figures.

Logistic regressions were used to identify factors associated with treatment outcomes at P value ≤ 0.05.

Results.

Out of 339 patients (197 males and 142 females) registered for antituberculosis treatment in Debre Tabor Health Center, only 303 patients were included in the treatment outcome analysis and 87.1% had successful treatment outcome while 12.9% had unsuccessful treatment outcome.

In the multivariate logistic regression analysis, the odds of successful treatment outcome were higher among patients ≥45 years of age (AOR=3.807, 95% CI: 1.155–12.544) and lower among females (AOR=0.347, 95% CI: 0.132–0.917), rural residents (AOR=0.342, 95% CI: 0.118–0.986), and negative smear result at the second month of treatment (AOR=0.056, 95% CI: 0.005–0.577) as compared to their counterparts.

Conclusion.

The treatment outcome of all forms of tuberculosis patients in Debre Tabor health center was satisfactory as expected from effective implementation of DOTS.

Although the observed successful treatment outcome was in agreement with the national target, follow-up of patients during the course of treatment to trace the treatment outcomes of transferred-out patients and assessment of other potential sociodemographic factors that could affect the treatment outcomes of TB patients were also recommended.