Hematological and Biochemistry Profile and Risk Factors Associated with Pulmonary Tuberculosis Patients in Guyana
Joint Authors
Kurup, Rajini
Flemming, Keon
Daniram, Sudish
Marks-James, Shenika
Roberts Martin, Roberta
Source
Tuberculosis Research and Treatment
Issue
Vol. 2016, Issue 2016 (31 Dec. 2016), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2016-04-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To evaluate the hematological and biochemistry profile of patients with or without HIV-TB at the Georgetown Chest Clinic, Guyana.
Methods.
An observational, laboratory based study was designed to assess the relationship of PTB and HIV with patients routine biochemical and hematological values.
The study was conducted during the period January 2013 to December 2014; a total sample size of 316 patients was enrolled following exclusion and inclusion criteria.
Results.
Mean age of study population was 40.1 ± 13.8 (95% CI 38.6–41.7) and most were between 40 and 49 age group (27.8%, 95% CI 23.2–33.0).
More males were in the study 74.4% (95% CI 69.3–78.8) than females 81% (95% CI 21.1–30.7).
30% (95% CI 25.3–35.3) had a sputum smear grade of 3+ and 62.5% (95% CI 47.0–75.7) showed a CD4 count <200.
The study demonstrated significantly low hemoglobin (Hb) 91.7% (95% CI 78.2–97.1), low WBC 27.8% (95% CI 15.8–44.0), high indirect bilirubin 7.4% (95% CI 2.1–23.3), ALT 41.8% (95% CI 28.4–56.7), and AST 72.2% (95% CI 57.3–83.3) among TB-HIV patients.
Homelessness RR (relative risk) 2.2 (95% CI 0.48–12.3), smoking RR 1.09 (95% CI 1.01–1.19), and gender (male) RR 1.2 (95% CI 0.61–2.26) were main associated risk factors.
Conclusions.
There is slight variation among PTB and PTB-HIV coinfected patients in some hematological and biochemistry parameters.
American Psychological Association (APA)
Kurup, Rajini& Flemming, Keon& Daniram, Sudish& Marks-James, Shenika& Roberts Martin, Roberta. 2016. Hematological and Biochemistry Profile and Risk Factors Associated with Pulmonary Tuberculosis Patients in Guyana. Tuberculosis Research and Treatment،Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1120263
Modern Language Association (MLA)
Kurup, Rajini…[et al.]. Hematological and Biochemistry Profile and Risk Factors Associated with Pulmonary Tuberculosis Patients in Guyana. Tuberculosis Research and Treatment No. 2016 (2016), pp.1-6.
https://search.emarefa.net/detail/BIM-1120263
American Medical Association (AMA)
Kurup, Rajini& Flemming, Keon& Daniram, Sudish& Marks-James, Shenika& Roberts Martin, Roberta. Hematological and Biochemistry Profile and Risk Factors Associated with Pulmonary Tuberculosis Patients in Guyana. Tuberculosis Research and Treatment. 2016. Vol. 2016, no. 2016, pp.1-6.
https://search.emarefa.net/detail/BIM-1120263
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1120263