Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates
Joint Authors
Jokanović, Vukoman
Čolović, Božana
Prokić, Bogomir Bolka
Tomanović, Nada
Popović Bajić, Marijana
Živković, Slavoljub
Source
Advances in Materials Science and Engineering
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-15
Country of Publication
Egypt
No. of Pages
6
Abstract EN
As an alternative to MTA, a new endodontic material based on hydroxyapatite and calcium silicates (ALBO-MPSA) has been synthesized, and its biocompatibility has been studied in many in vitro and in vivo studies.
The current study aims to evaluate a subchronic systemic toxicity of ALBO-MPSA on the rat animal model, as a continuation of the previous studies.
Biochemical parameters of blood and histological parameters of the liver, kidneys, and spleen of the rats were analyzed after 120 days of consumption of the aqueous extract of ALBO-MPSA.
The results showed no myelotoxic effect or autoimmune effect on peripheral blood cells and no pathological effect on the liver, kidney, and spleen tissues.
Besides, no changes in the skin and hair of the rats, neither the change in the consumption of food and water, nor the change in their usual behavior were noticed during the experiment.
American Psychological Association (APA)
Jokanović, Vukoman& Čolović, Božana& Prokić, Bogomir Bolka& Tomanović, Nada& Popović Bajić, Marijana& Živković, Slavoljub. 2018. Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates. Advances in Materials Science and Engineering،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1122054
Modern Language Association (MLA)
Jokanović, Vukoman…[et al.]. Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates. Advances in Materials Science and Engineering No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1122054
American Medical Association (AMA)
Jokanović, Vukoman& Čolović, Božana& Prokić, Bogomir Bolka& Tomanović, Nada& Popović Bajić, Marijana& Živković, Slavoljub. Subchronic Systemic Toxicity of New Endodontic Material Based on Calcium Hydroxyapatite and Calcium Silicates. Advances in Materials Science and Engineering. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1122054
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1122054
