Neural Mechanisms of Reward Prediction Error in Autism Spectrum Disorder
Joint Authors
Mosner, Maya G.
McLaurin, R. Edward
Kinard, Jessica L.
Hakimi, Shabnam
Parelman, Jacob
Shah, Jasmine S.
Bizzell, Joshua
Greene, Rachel K.
Cernasov, Paul M.
Walsh, Erin
Addicott, Merideth A.
Eisenlohr-Moul, Tory
Carter, R. McKell
Dichter, Gabriel S.
Source
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-07-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Few studies have explored neural mechanisms of reward learning in ASD despite evidence of behavioral impairments of predictive abilities in ASD.
To investigate the neural correlates of reward prediction errors in ASD, 16 adults with ASD and 14 typically developing controls performed a prediction error task during fMRI scanning.
Results revealed greater activation in the ASD group in the left paracingulate gyrus during signed prediction errors and the left insula and right frontal pole during thresholded unsigned prediction errors.
Findings support atypical neural processing of reward prediction errors in ASD in frontostriatal regions critical for prediction coding and reward learning.
Results provide a neural basis for impairments in reward learning that may contribute to traits common in ASD (e.g., intolerance of unpredictability).
American Psychological Association (APA)
Mosner, Maya G.& McLaurin, R. Edward& Kinard, Jessica L.& Hakimi, Shabnam& Parelman, Jacob& Shah, Jasmine S.…[et al.]. 2019. Neural Mechanisms of Reward Prediction Error in Autism Spectrum Disorder. Autism Research and Treatment،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1122427
Modern Language Association (MLA)
Mosner, Maya G.…[et al.]. Neural Mechanisms of Reward Prediction Error in Autism Spectrum Disorder. Autism Research and Treatment No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1122427
American Medical Association (AMA)
Mosner, Maya G.& McLaurin, R. Edward& Kinard, Jessica L.& Hakimi, Shabnam& Parelman, Jacob& Shah, Jasmine S.…[et al.]. Neural Mechanisms of Reward Prediction Error in Autism Spectrum Disorder. Autism Research and Treatment. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1122427
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1122427