Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier
Joint Authors
Gharbavi, Mahmoud
Amani, Jafar
Kheiri-Manjili, Hamidreza
Danafar, Hossein
Sharafi, Ali
Source
Advances in Pharmacological and Pharmaceutical Sciences
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-12-11
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Niosomes (the nonionic surfactant vesicles), considered as novel drug delivery systems, can improve the solubility and stability of natural pharmaceutical molecules.
They are established to provide targeting and controlled release of natural pharmaceutical compounds.
Many factors can influence on niosome construction such as the preparation method, type and amount of surfactant, drug entrapment, temperature of lipids hydration, and the packing factor.
The present review discusses about the most important features of niosomes such as their diverse structures, the different preparation approaches, characterization techniques, factors that affect their stability, their use by various routes of administration, their therapeutic applications in comparison with natural drugs, and specially the brain targeting with niosomes-ligand conjugation.
It also provides recent data about the various types of ligand agents which make available active targeting drug delivery to the central neuron system.
This system has an optimistic upcoming in pharmaceutical uses, mostly with the improving availability of innovative schemes to overcome blood-brain barrier and targeting the niosomes to the brain.
American Psychological Association (APA)
Gharbavi, Mahmoud& Amani, Jafar& Kheiri-Manjili, Hamidreza& Danafar, Hossein& Sharafi, Ali. 2018. Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier. Advances in Pharmacological and Pharmaceutical Sciences،Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1122792
Modern Language Association (MLA)
Gharbavi, Mahmoud…[et al.]. Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier. Advances in Pharmacological and Pharmaceutical Sciences No. 2018 (2018), pp.1-15.
https://search.emarefa.net/detail/BIM-1122792
American Medical Association (AMA)
Gharbavi, Mahmoud& Amani, Jafar& Kheiri-Manjili, Hamidreza& Danafar, Hossein& Sharafi, Ali. Niosome: A Promising Nanocarrier for Natural Drug Delivery through Blood-Brain Barrier. Advances in Pharmacological and Pharmaceutical Sciences. 2018. Vol. 2018, no. 2018, pp.1-15.
https://search.emarefa.net/detail/BIM-1122792
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1122792