Absence of Association between Preoperative Estimated Glomerular Filtration Rates and Postoperative Outcomes following Elective Gastrointestinal Surgeries: A Prospective Cohort Study
Joint Authors
Kamarajah, Sivesh K.
Barmayehvar, Behrad
Sowida, Mustafa
Adlan, Amirul
Reihill, Christina
Ellahee, Parvez
Source
Anesthesiology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Preoperative risk stratification and optimising care of patients undergoing elective surgery are important to reduce the risk of postoperative outcomes.
Renal dysfunction is becoming increasingly prevalent, but its impact on patients undergoing elective gastrointestinal surgery is unknown although much evidence is available for cardiac surgery.
This study aimed to investigate the impact of preoperative estimated glomerular filtration rate (eGFR) and postoperative outcomes in patients undergoing elective gastrointestinal surgeries.
Methods.
This prospective study included consecutive adult patients undergoing elective gastrointestinal surgeries attending preassessment screening (PAS) clinics at the Queen Elizabeth Hospital Birmingham (QEHB) between July and August 2016.
Primary outcome measure was 30-day overall complication rates and secondary outcomes were grade of complications, 30-day readmission rates, and postoperative care setting.
Results.
This study included 370 patients, of which 11% (41/370) had eGFR of <60 ml/min/1.73 m2.
Patients with eGFR < 60 ml/min/1.73 m2 were more likely to have ASA grade 3/4 (p<0.001) and >2 comorbidities (p<0.001).
Overall complication rates were 15% (54/370), with no significant difference in overall (p=0.644) and major complication rates (p=0.831) between both groups.
In adjusted models, only surgery grade was predictive of overall complications.
Preoperative eGFR did not impact on overall complications (HR: 0.89, 95% CI: 0.45–1.54; p=0.2).
Conclusions.
Preoperative eGFR does not appear to impact on postoperative complications in patients undergoing elective gastrointestinal surgeries, even when stratified by surgery grade.
These findings will help preassessment clinics in risk stratification and optimisation of perioperative care of patients.
American Psychological Association (APA)
Kamarajah, Sivesh K.& Barmayehvar, Behrad& Sowida, Mustafa& Adlan, Amirul& Reihill, Christina& Ellahee, Parvez. 2018. Absence of Association between Preoperative Estimated Glomerular Filtration Rates and Postoperative Outcomes following Elective Gastrointestinal Surgeries: A Prospective Cohort Study. Anesthesiology Research and Practice،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1122885
Modern Language Association (MLA)
Kamarajah, Sivesh K.…[et al.]. Absence of Association between Preoperative Estimated Glomerular Filtration Rates and Postoperative Outcomes following Elective Gastrointestinal Surgeries: A Prospective Cohort Study. Anesthesiology Research and Practice No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1122885
American Medical Association (AMA)
Kamarajah, Sivesh K.& Barmayehvar, Behrad& Sowida, Mustafa& Adlan, Amirul& Reihill, Christina& Ellahee, Parvez. Absence of Association between Preoperative Estimated Glomerular Filtration Rates and Postoperative Outcomes following Elective Gastrointestinal Surgeries: A Prospective Cohort Study. Anesthesiology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1122885
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1122885