Early Infant Diagnosis Sample Management in Mashonaland West Province, Zimbabwe, 2017
Joint Authors
Mugauri, Hamufare
Mugurungi, Owen
Chadambuka, Addmore
Juru, Tsitsi
Gombe, Notion Tafara
Shambira, Gerald
Tshimanga, Mufuta
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
In 2016, Mashonaland West Province had 7.4% (520) dried blood spot (DBS) samples for early infant diagnosis (EID) rejected by the Zimbabwe National Microbiology Reference Laboratory (NMRL).
The samples were suboptimal, delaying treatment initiation for HIV-infected children.
EID is the entry point to HIV treatment services in exposed infants.
We determined reasons for DBS sample rejections and suggested solutions.
Methods.
A cause-effect analysis, modelled on Ishikawa, was used to identify factors impacting DBS sample quality.
Interviewer-administered questionnaires and evaluation of sample collection process, using Standard Operating Procedure (SOP) was conducted.
Rejected samples were reviewed.
Epi Info™ was used to analyze findings.
Results.
Eleven (73.3%) facilities did not adhere to SOP and (86.7%) did not evaluate DBS sample quality before sending for testing.
Delayed feedback (up to 4 weeks) from NMRL extended EID delay for 14 (93.3%) of the facilities.
Of the 53 participants, 62% knew valid sample identification.
Insufficient samples resulted in most rejections (77.9%).
Lack of training (94.3%) and ineffective supervision (69.8%) were also cited.
Conclusion.
Sample rejections could have been averted through SOP adherence.
Ineffective supervision, exacerbated by delayed communication of rejections, extended EID delay, disadvantaging potential ART beneficiaries.
Following this study, enhanced quality control through perstage evaluations was recommended to enhance DBS sample quality.
American Psychological Association (APA)
Mugauri, Hamufare& Mugurungi, Owen& Chadambuka, Addmore& Juru, Tsitsi& Gombe, Notion Tafara& Shambira, Gerald…[et al.]. 2018. Early Infant Diagnosis Sample Management in Mashonaland West Province, Zimbabwe, 2017. AIDS Research and Treatment،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1122920
Modern Language Association (MLA)
Mugauri, Hamufare…[et al.]. Early Infant Diagnosis Sample Management in Mashonaland West Province, Zimbabwe, 2017. AIDS Research and Treatment No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1122920
American Medical Association (AMA)
Mugauri, Hamufare& Mugurungi, Owen& Chadambuka, Addmore& Juru, Tsitsi& Gombe, Notion Tafara& Shambira, Gerald…[et al.]. Early Infant Diagnosis Sample Management in Mashonaland West Province, Zimbabwe, 2017. AIDS Research and Treatment. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1122920
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1122920