The effect of chitosan on osteogenesis, histological study in rabbits

Abstract EN

Bone regeneration is a major limiting factor in oral surgery regenerative therapy.

The concept of guided tissue regeneration has provided the strongest evidence that tissue healing can be influenced exogenously by wound management.

At the cellular level, the existence of osteoprogenitors with the capacity to produce bone in the wound site and the potential to exogenously influence the behavior of these cells offers the opportunity to further enhance regenerative wound healing.

Chitosan, with a chemical structure similar to hyaluronate, has been implicated as a wound healing agent.

The purpose of this research was to evaluate the effect of chitosan on osteoblast differentiation and bone formation in vitro.