Immune-Related Concepts in Biology and Treatment of Germ-Cell Tumors
Joint Authors
De Giorgi, Ugo
Chovanec, Michal
Mego, Michal
Source
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-13
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Germ-cell tumors (GCTs) are highly curable with chemotherapy.
Salvage chemotherapy or surgery can cure a proportion of patients, but the ones failing these treatments will die of their disease in the young age.
Immune checkpoint pathways are emerging as powerful targetable biomarkers, and a significant preclinical and clinical research is underway to widen our knowledge and expand the treatment possibilities with immune therapy.
The concept of immune modulation that was currently adopted in many solid tumors is understudied in GCTs.
Herein, we summarize the current knowledge of published literature discussing the immune mechanisms and immune therapy in GCTs.
American Psychological Association (APA)
Chovanec, Michal& De Giorgi, Ugo& Mego, Michal. 2018. Immune-Related Concepts in Biology and Treatment of Germ-Cell Tumors. Advances in Urology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1123012
Modern Language Association (MLA)
Chovanec, Michal…[et al.]. Immune-Related Concepts in Biology and Treatment of Germ-Cell Tumors. Advances in Urology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1123012
American Medical Association (AMA)
Chovanec, Michal& De Giorgi, Ugo& Mego, Michal. Immune-Related Concepts in Biology and Treatment of Germ-Cell Tumors. Advances in Urology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1123012
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1123012